Evidence map›Paper›PMID 31964929›Full record

ArticleScientific reports2020

Initial report of γ-aminobutyric acidergic locomotion regulatory system and its 3-mercaptopropionic acid-sensitivity in metamorphic juvenile of sea urchin, Hemicentrotus pulcherrimus.

Hideki Katow, Hiromi Yoshida, Masato Kiyomoto

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hideki KatowResearch Center for Marine Biology, Tohoku University, Asamushi, Aomori, 039-3501, Japan. h.tkatow@d6.dion.ne.jp.
Hiromi YoshidaInstitute of Development, Aging and Cancer, Tohoku University, Sendai, 980-8575, Japan.
Masato KiyomotoInstitute of Development, Aging and Cancer, Tohoku University, Sendai, 980-8575, Japan.
Tohoku University · JPOchanomizu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The γ-aminobutyric acid (GABA) signal transmission system (GSTS) contributes to larval swimming through the regulation of ciliary beating. However, whether this system also contributes to the primary podia (PP)-generated motility of juveniles remained unclear. The present study aimed to elucidate the involvement of the GSTS in the motility of metamorphic juveniles (juveniles) (1) by immunohistochemically elucidating the location of molecular constituents of the PP, and (2) by inhibiting the activity of GΑΒΑ decarboxylase (GAD) with 3-mercaptopropionic acid (3-MPA). During metamorphosis, the echinus rudiment protrudes its PP out of the body surface in 8-arm plutei. The PP expresses immunopositive signal (-IS) of GAD, GABA, GABA

Indexed as

3-Mercaptopropionic AcidAnimalsBehavior, AnimalBiomarkersgamma-Aminobutyric AcidGene Expression Regulation, DevelopmentalGlutamate DecarboxylaseHemicentrotusLocomotionMetamorphosis, Biological3-Mercaptopropionic AcidBiomarkersgamma-Aminobutyric AcidGlutamate Decarboxylase

Identifiers

PMID31964929
PMCPMC6972954
OpenAlexW3001969747

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.