ArticleProceedings of the National Academy of Sciences of the United States of America2020
Pressure sensing through Piezo channels controls whether cells migrate with blebs or pseudopods.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed.
- Article
- Biophysics of lumen morphogenesis.Development (Cambridge, England) · 2026Review
- Chemical and Mechanical Regulation of Leukocyte Migration.Cold Spring Harbor perspectives in biology · 2026Review
- A role for PaxB in regulating blebbing: experimental insights and theoretical perspectives from Dictyostelium discoideum.BMC molecular and cell biology · 2026Article
- Chemotactic motion of coronin-null cells with impaired actin turnover.BMC molecular and cell biology · 2026Article
- Article
- Review
- Review
- Regulation of PIEZO1 channel force sensitivity by interblade handshaking.Science advances · 2025Article
- Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis.Cytoskeleton (Hoboken, N.J.) · 2025Review
- Confinement by Liquid-Liquid Interface Replicates In Vivo Neutrophil Deformations and Elicits Bleb-Based Migration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Frictiotaxis underlies focal adhesion-independent durotaxis.Nature communications · 2025Article
- Piezo, Nephrocyte Function, and Slit Diaphragm Maintenance in Drosophila.Journal of the American Society of Nephrology : JASN · 2025Article
- Nuclear Envelope Dynamics inCells · 2025Review
- Physical principles and mechanisms of cell migration.npj biological physics and mechanics · 2025Review
- The biophysics of cell motility through mechanochemically challenging environments.Current opinion in cell biology · 2024Review
- Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation.Trends in cell biology · 2024Review
- Blebology: principles of bleb-based migration.Trends in cell biology · 2024Review
- Piezo regulates epithelial topology and promotes precision in organ size control.Cell reports · 2024Article
- Ion Signaling in Cell Motility and Development inBiomolecules · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Blebs and pseudopods can both power cell migration, with blebs often favored in tissues, where cells encounter increased mechanical resistance. To investigate how migrating cells detect and respond to mechanical forces, we used a "cell squasher" to apply uniaxial pressure to
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.