Evidence map›Paper›PMID 31964788›Full record

ArticleAntimicrobial agents and chemotherapy2020

Thuli Mthiyane, James Millard, John Adamson, Yusentha Balakrishna, Cathy Connolly, Andrew Owen, Roxana Rustomjee, Keertan Dheda, Helen McIlleron, Alexander S Pym

Abstract readMulticenter Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. A Nanopore Sequencing-based Pharmacogenomic Panel to Personalize Tuberculosis Drug Dosing.American journal of respiratory and critical care medicine · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Severe efavirenz associated neurotoxicity: A retrospective cohort study.Southern African journal of infectious diseases · 2023
    Article
  13. Article
  14. Case Study 10: A Case to Investigate Acetyl Transferase Kinetics.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thuli MthiyaneSouth African Medical Research Council, Durban, South Africa thuli.mthiyane@mrc.ac.za.
James MillardWellcome Trust Liverpool Glasgow Centre for Global Health Research, Liverpool, United Kingdom.
John AdamsonAfrica Health Research Institute, Durban, South Africa.
Yusentha BalakrishnaSouth African Medical Research Council, Biostatistics Department, Durban, South Africa.
Cathy ConnollySouth African Medical Research Council, Biostatistics Department, Durban, South Africa.
Andrew OwenDepartment of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom.
Roxana RustomjeeSouth African Medical Research Council, Durban, South Africa.
Keertan DhedaLung Infection and Immunity Unit, Division of Pulmonology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Helen McIlleronDivision of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Alexander S PymSouth African Medical Research Council, Durban, South Africa.

Funding

Wellcome Trust
6 · The paper itself

Abstract

The distribution of

Indexed as

AcetylationAdolescentAdultAIDS-Related Opportunistic InfectionsAntitubercular AgentsArylamine N-AcetyltransferaseBlack PeopleFemaleGene FrequencyGenotypeHaplotypesHumansIsoniazidMaleMiddle AgedSouth AfricaacetylisoniazidAntitubercular AgentsArylamine N-AcetyltransferaseIsoniazidNAT2 protein, humanacetylationdrug metabolismHIVisoniazidN-acetyltransferasepharmacogeneticspharmacokineticstuberculosis

Identifiers

PMID31964788
PMCPMC7179278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.