Evidence map›Paper›PMID 31964766›Full record

ArticlemSystems2020

Planktonic and Sessile Artificial Colonic Microbiota Harbor Distinct Composition and Reestablish Differently upon Frozen and Freeze-Dried Long-Term Storage.

Lea Bircher, Clarissa Schwab, Annelies Geirnaert, Anna Greppi, Christophe Lacroix

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Applied and environmental microbiology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Microbiome research reports · 2023
    Review
  10. Review
  11. Article
  12. Surface Properties ofMicroorganisms · 2021
    Article
  13. mSystems · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lea BircherLaboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zürich, Zurich, Switzerland.
Clarissa SchwabLaboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zürich, Zurich, Switzerland.
Annelies GeirnaertLaboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zürich, Zurich, Switzerland.
Anna GreppiLaboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zürich, Zurich, Switzerland.
Christophe LacroixLaboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zürich, Zurich, Switzerland christophe.lacroix@hest.ethz.ch.
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilm-associated, sessile communities represent the major bacterial lifestyle, whereas planktonic cells mainly appear during initial colonization of new surfaces. Previous research, mainly performed with pathogens, demonstrated increased environmental stress tolerance of biofilm-growing compared to planktonic bacteria. The lifestyle-specific stress response of colonic microbiota, both natural and fermentation produced, has not been addressed before. Planktonic and sessile "artificial" colonic microbiota delivered by PolyFermS continuous fermentation models can provide a controllable and reproducible alternative to fecal transplantation in treating gastrointestinal disorders. We therefore characterized planktonic and sessile microbiota produced in two PolyFermS models inoculated with immobilized fecal microbiota and comparatively tested their levels of tolerance of frozen storage (-80°C) and freeze-dried storage (4°C) for 9 months to mimic preservation strategies for therapeutic applications. Sessile microbiota harbored next to shared taxa a unique community distinguishable from planktonic microbiota.

Indexed as

bacterial lifestylecolonic microbiotacryopreservationFMTlyophilization

Identifiers

PMID31964766
PMCPMC6977070
OpenAlexW3001439101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.