Evidence map›Paper›PMID 31964747›Full record

ArticleInfection and immunity2020

Inhibition of tRNA Synthetases Induces Persistence in

Nathan D Hatch, Scot P Ouellette

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Repurposing epetraborole to combatAntimicrobial agents and chemotherapy · 2026
    Article
  3. Article
  4. Disrupted Cervicovaginal Microbiota: Its Role inInternational journal of molecular sciences · 2025
    Review
  5. Genome-wide Screening of the Escherichia coli Keio Knockout Collection Identifies Genetic Determinants of Epetraborole Hypersusceptibility.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Association ofFrontiers in cellular and infection microbiology · 2023
    Article
  13. Review
  14. A Review of Antibiotic Efficacy in COVID-19 Control.Journal of immunology research · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nathan D HatchDepartment of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Scot P OuelletteDepartment of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA scot.ouellette@unmc.edu.ORCID 0000-0002-3721-6839
University of Nebraska Medical Center · US

Funding

Regulatory Role of Tandem Tryptophan Codons in Chlamydial PersistenceR01AI132406 · NIAID · WASHINGTON STATE UNIVERSITY · PI CARABEO, REY A, OUELLETTE, SCOT P · 2019 to 2023
$2.9M
NIAID NIH HHS R01 AI132406
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptation, PhysiologicalGene Expression Regulation, BacterialAmino Acyl-tRNA SynthetasesCell LineChlamydia InfectionsChlamydia trachomatisChlamydophila pneumoniaeEnzyme InhibitorsHost-Pathogen InteractionsHumansIndolesLeucineModels, BiologicalTranscription, GeneticTryptophanAmino Acyl-tRNA SynthetasesEnzyme InhibitorsIndolesindolmycinLeucineTryptophanamino acid limitationamino acid starvationChlamydiacodon-dependent transcriptionIFN-γleucinepersistencetRNA synthetase inhibitorstRNA synthetasestryptophan

Identifiers

PMID31964747
PMCPMC7093126
OpenAlexW3002823268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.