Evidence map›Paper›PMID 31964735›Full record

ArticlemBio2020

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.

Nora Steffens, Cornelia Beuter-Gunia, Elisabeth Kravets, Artur Reich, Larissa Legewie, Klaus Pfeffer, Daniel Degrandi

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Lymphotoxin beta receptorInfection and immunity · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Integrative modeling of guanylate binding protein dimers.Protein science : a publication of the Protein Society · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Immune response against toxoplasmosis-some recent updates RH:International journal of immunopathology and pharmacology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nora Steffens *Institute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Cornelia Beuter-Gunia *Institute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Elisabeth KravetsInstitute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Artur ReichInstitute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Larissa LegewieInstitute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Klaus PfefferInstitute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Daniel DegrandiInstitute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany daniel.degrandi@hhu.de.ORCID 0000-0001-6281-0357
Heinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Members of the murine guanylate-binding protein family (mGBP) are induced by interferon gamma (IFN-γ) and have been shown to be important factors in cell-autonomous immunity toward the intracellular pathogen

Indexed as

Host-Parasite InteractionsAnimalsBiomarkersCytokinesDisease Models, AnimalGTP-Binding ProteinsImmunity, CellularMiceMice, KnockoutProtein TransportToxoplasmaToxoplasmosisBiomarkersCytokinesGTP-Binding Proteinscell-autonomous immunityguanylate-binding proteinshost-pathogen interactioninterferonsmGBP7Toxoplasma gondii

Identifiers

PMID31964735
PMCPMC6974569
OpenAlexW3001183284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.