Evidence map›Paper›PMID 31964733›Full record

ArticlemBio2020

RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria.

Xiaolong Shao, Weitong Zhang, Mubarak Ishaq Umar, Hei Yuen Wong, Zijing Seng, Yingpeng Xie, Yingchao Zhang, Liang Yang, Chun Kit Kwok, Xin Deng

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 80 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Regulation of the Expression ofAntibiotics (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Profiling RNA G-Quadruplexes In vivo.Current protocols · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Gas-sensing riboceptors.RNA biology · 2024
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Xiaolong Shao *Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Weitong Zhang *Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Mubarak Ishaq Umar *Department of Chemistry, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Hei Yuen WongDepartment of Chemistry, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Zijing SengSingapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore.
Yingpeng XieDepartment of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Yingchao ZhangDepartment of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Liang YangSchool of Medicine, Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, China.ORCID 0000-0002-2362-0128
Chun Kit KwokDepartment of Chemistry, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China ckkwok42@cityu.edu.hk xindeng@cityu.edu.hk.
Xin DengDepartment of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China ckkwok42@cityu.edu.hk xindeng@cityu.edu.hk.
City University of Hong Kong · HKNanyang Technological University · SGSouthern University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guanine (G)-rich sequences in RNA can fold into diverse RNA G-quadruplex (rG4) structures to mediate various biological functions and cellular processes in eukaryotic organisms. However, the presence, locations, and functions of rG4s in prokaryotes are still elusive. We used QUMA-1, an rG4-specific fluorescent probe, to detect rG4 structures in a wide range of bacterial species both

Indexed as

Gene Expression Regulation, BacterialG-QuadruplexesBacteriaBiofilmsGene Expression ProfilingHigh-Throughput Nucleotide SequencingHumansRNARNAbacteriagene regulationnucleic acid structuresprokaryotesRNA G-quadruplexes (rG4)transcriptome-wide

Identifiers

PMID31964733
PMCPMC6974567
OpenAlexW3000889356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.