Evidence map›Paper›PMID 31964711›Full record

ArticleJournal of cell science2020

RHOA-mediated mechanical force generation through Dectin-1.

Rohan P Choraghe, Tomasz Kołodziej, Alan Buser, Zenon Rajfur, Aaron K Neumann

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Building the phagocytic cup on an actin scaffold.Current opinion in cell biology · 2022
    Review
  9. Article
  10. Immune cells fold and damage fungal hyphae.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Dectin-1-Mediated DC-SIGN Recruitment toLife (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Rohan P ChoragheDepartment of Pathology, University of New Mexico, Albuquerque, NM 87131, USA.
Tomasz KołodziejDepartment of Pathology, University of New Mexico, Albuquerque, NM 87131, USA.
Alan BuserDepartment of Pathology, University of New Mexico, Albuquerque, NM 87131, USA.
Zenon RajfurInstitute of Physics, Jagiellonian University, Krakow 30-348, Poland.
Aaron K NeumannDepartment of Pathology, University of New Mexico, Albuquerque, NM 87131, USA akneumann@salud.unm.edu.ORCID 0000-0002-1689-8324
University of New Mexico · USJagiellonian University · PL

Funding

UNM TRAININGP50GM085273 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI EDWARDS, JEREMY S · 2009 to 2018
$26.1M
Nano and Microscale Molecular Machines for Innate Immune Sensing of CandidaR01AI116894 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI NEUMANN, AARON KURT · 2015 to 2019
$1.9M
NIAID NIH HHS R01 AI116894NIGMS NIH HHS P50 GM085273
6 · The paper itself

Abstract

Dendritic cell-associated C-type lectin 1 (Dectin-1, also known as CLEC7A) is an innate immune pattern recognition receptor that recognizes β-glucan on the

Indexed as

Lectins, C-TypePhagocytosisCandida albicansDectin-1HEK293 CellsHumansRespiratory BurstrhoA GTP-Binding ProteinCLEC7A protein, humanDectin-1Lectins, C-TyperhoA GTP-Binding ProteinRHOA protein, humanCandida albicansDectin-1Fungal pathogenMechanobiologyRHOA

Identifiers

PMID31964711
PMCPMC7063837
OpenAlexW3003004354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.