Evidence map›Paper›PMID 31964703›Full record

ArticleJournal of cell science2020

The gap junction protein connexin 43 controls multiple aspects of cranial neural crest cell development.

Karyn Jourdeuil, Lisa A Taneyhill

Open access · bronzeAbstract readLecture
In one paragraph

Article in Journal of cell science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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  13. Cell Adhesion Molecules in Plasticity and Metastasis.Molecular cancer research : MCR · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Karyn JourdeuilDepartment of Animal and Avian Sciences, University of Maryland, College Park, MD 20742, USA.
Lisa A TaneyhillDepartment of Animal and Avian Sciences, University of Maryland, College Park, MD 20742, USA ltaney@umd.edu.ORCID 0000-0002-8630-2514
University of Maryland, College Park · US

Funding

Neural crest and placode cell interactions during cranial gangliogenesisR01DE024217 · NIDCR · UNIV OF MARYLAND, COLLEGE PARK · PI TANEYHILL, LISA A · 2014 to 2018
$1.9M
NIDCR NIH HHS R01 DE024217
6 · The paper itself

Abstract

Gap junctions are intercellular channels between cells that facilitate cell-cell communication. Connexin 43 (Cx43; also known as GJA1), the predominant gap junction protein in vertebrates, is expressed in premigratory cranial neural crest cells and is maintained throughout the neural crest cell epithelial-to-mesenchymal transition (EMT), but its function in these cells is unknown. To this end, we used a combination of

Indexed as

Connexin 43Neural CrestAnimalsCell DifferentiationConnexinsGap JunctionsNeural TubeConnexin 43ConnexinsConnexin 43Epithelial-to-mesenchymal transitionGap junctionNeural crest

Identifiers

PMID31964703
PMCPMC7044449
OpenAlexW3002383470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.