ArticleNutrition journal2020
Geographical influences on the iodine status in pregnant women, neonates, and school-age children in China.
Article in Nutrition journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Prevalence of thyroid disorders in inland and coastal populations: A systematic review.Frontiers in endocrinology · 2026Pooled it
- Stage-specific variations in urinary and salt iodine among pregnant women in Beijing.Frontiers in nutrition · 2026Article
- Plant-derived nutritional components in thyroid disease-related neuropsychiatric disorders: mechanistic insights and advances.Frontiers in nutrition · 2026Review
- Global, regional, and national burden of iodine deficiency for women of reproductive age, 1990-2021: a systematic analysis based on the Global Burden of Disease Study 2021.Frontiers in nutrition · 2025Article
- Impact of iodine nutritional levels in urban and rural pregnant women on neonatal growth indicators: a cohort study in Xinjiang, China.Frontiers in nutrition · 2025Article
- Thyroglobulin as a Sensitive Biomarker of Iodine Status in Mildly and Moderately Iodine-Deficient Pregnant Women.Biological trace element research · 2024Article
- Pregnant women at risk for iodine deficiency but adequate iodine intake in school-aged children of Zhejiang Province, China.Environmental geochemistry and health · 2024Article
- Iodine in household cooking salt no longer plays a crucial role in iodine status of residents in Tianjin, China.European journal of nutrition · 2022Article
- Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations.Frontiers in nutrition · 2022Article
- Prevalence of urinary iodine concentration among school children: in Dessie City, Ethiopia.BMC pediatrics · 2021Article
- Low Iodine Intake May Decrease Women's Fecundity: A Population-Based Cross-Sectional Study.Nutrients · 2021Article
- Geographical influences on thyroid abnormalities in adult population from iodine-replete regions: a cross-sectional study.Scientific reports · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPregnant women, neonates, and school-age children are vulnerable to iodine deficiency. The iodine contents in the environment (drinking water and household salt for cooking) vary by geographical location in China. The aim of this study was to assess the iodine status in vulnerable groups from different geographical zones and analyze the iodine content in household salt and drinking water from these zones.
methodsIn coastal and inland regions of Zhejiang Province, China, samples of spot urine, drinking water, and household salt for cooking from both pregnant women and school-age children were determined for iodine concentration between 2017 and 2018. Thyroid-stimulating hormone (TSH) levels from neonates born between 2014 and 2015 were acquired from the Newborns Screening Information System. The iodine status of the vulnerable populations was assessed according to the criteria recommended by the World Health Organization.
resultsThe median UIC of pregnant women was significantly lower in the coastal region (113.0 μg/L) than the inland region (134.9 μg/L; p < 0.001). The median UICs of pregnant women from these two regions were below the lower optimal iodine cutoff level of 150 μg/L. The percentage of neonates with elevated TSH (> 5 mIU/L) was significantly higher in the coastal region (15.8%) than the inland region (10.5%; p < 0.001). The percentage of neonates with elevated TSH from each region decreased within the range of mild iodine deficiency of 3-19.9%. The median UIC of the coastal school-age children was 156.0 μg/L, and the median UIC of inland children was 181.5 μg/L. Both medians fell within the recommended optimal iodine range of 100-299 μg/L. The iodine concentrations in drinking water varied from 1.0 μg/L in the inland region to 2.0 μg/L in the coastal region. The proportion of households that consumed iodized salt was lower in the coastal region (nearly 65%) than the inland region (approximately 95%).
conclusionsIn these two regions with low iodine contents in drinking water, both pregnant women and neonates were iodine-deficient, although school-age children were iodine-sufficient. Urgent efforts are needed to improve the iodine status of pregnant women and neonates.
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