ArticleBMC pregnancy and childbirth2020
The diagnosis and treatment of adrenocortical carcinoma in pregnancy: a case report.
Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 6 citations in OpenAlex.
- Adrenocortical carcinoma in a 10-month-old infant: A literature review and a rare case report.Annals of medicine and surgery (2012) · 2023Article
- Adrenocortical Carcinoma in Pregnancy: The First Case Report in Mexico and Review of the Literature.Case reports in oncologyArticle
- Adrenocortical Carcinoma With Cushing's Syndrome and Hyperandrogenism in a 28-Year-Old Pregnant Female.AACE clinical case reportsArticle
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6 authors at 1 institution in 1 country.
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Abstract
backgroundPregnancy complicated with adrenocortical carcinoma (ACC) is a sporadic syndrome that is characterized by hypertension, uncontrolled hypokalemia, severe heart failure, premature delivery and other adverse effects. The clinical presentation of adrenocortical carcinoma is vague and nonspecific, it is challenging to identify complications of pregnancy with adrenocortical carcinoma. Here we present a case of adrenocortical carcinoma during pregnancy. We describe how to distinguish secondary hypertension from other conditions and the importance of timely detection and treatment of such patients. CASE PRESENTATION: A 22-year-old woman 30 weeks pregnant was hospitalized with uncontrolled hypertension and hypokalemia. An ultrasound examination of the right adrenal gland revealed a large mass. She underwent transabdominal adrenalectomy, and histopathology from the sample removed revealed an adrenocortical carcinoma. Five days after surgery, the patient had a premature rupture of the fetal membranes and gave birth to a newborn girl via vaginal delivery at 32 weeks of gestation. The newborn was transferred to the neonatal pediatrics ward, and the woman started receiving chemotherapy.
conclusionsPregnancy with adrenocortical carcinoma is a rare condition. This case alerts the obstetricians that analysis of hypertension, hypokalemia, the plasma level and circadian rhythm of plasma cortisol provides a strategy to diagnose adrenocortical carcinoma during pregnancy.
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