Evidence map›Paper›PMID 31964272›Full record

ArticleJournal of the Royal Society, Interface2020

Evaluation of burst release and sustained release of pioglitazone-loaded fibrous mats on diabetic wound healing: an

Muhammet Emin Cam, Sila Yildiz, Hussain Alenezi, Sumeyye Cesur, Gul Sinemcan Ozcan, Gokce Erdemir, Ursula Edirisinghe, Dilek Akakin, Durdane Serap Kuruca, Levent Kabasakal and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 105 citations in OpenAlex.

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  19. Casein fibres for wound healing.Journal of the Royal Society, Interface · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Muhammet Emin CamDepartment of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK.
Sila YildizCentre for Discovery Brain Sciences, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK.
Hussain AleneziDepartment of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK.
Sumeyye CesurCenter for Nanotechnology and Biomaterials Research, Marmara University, Istanbul 34722, Turkey.
Gul Sinemcan OzcanDepartment of Histology and Embryology, Faculty of Medicine, Marmara University, Istanbul 34854, Turkey.
Gokce ErdemirDepartment of Molecular Medicine, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul 34093, Turkey.
Ursula EdirisingheAccident and Emergency Department, Hillingdon Hospital, NHS Foundation Trust, Pield Heath Road, Uxbridge UB8 3NN, UK.
Dilek AkakinDepartment of Histology and Embryology, Faculty of Medicine, Marmara University, Istanbul 34854, Turkey.
Durdane Serap KurucaDepartment of Physiology, Faculty of Medicine, Istanbul University, Istanbul 34093, Turkey.
Levent KabasakalDepartment of Pharmacology, Faculty of Pharmacy, Marmara University, Istanbul 34716, Turkey.
Oguzhan GunduzCenter for Nanotechnology and Biomaterials Research, Marmara University, Istanbul 34722, Turkey.
Mohan EdirisingheDepartment of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK.
Marmara University · TRIstanbul University · TRUniversity College London · GBHillingdon Hospital · GBPublic Authority for Applied Education and Training · KWUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to provide more effective treatment strategies for the rapid healing of diabetic wounds, novel therapeutic approaches need to be developed. The therapeutic potential of peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist pioglitazone hydrochloride (PHR) in two different release kinetic scenarios, burst release and sustained release, was investigated and compared with

Indexed as

Diabetes Mellitus, ExperimentalAnimalsDelayed-Action PreparationsMiceNIH 3T3 CellsPioglitazoneRatsWound HealingDelayed-Action PreparationsPioglitazoneburst releasediabetic wound healingdrug deliveryfibrespioglitazonesustained release

Identifiers

PMID31964272
PMCPMC7014808
OpenAlexW3002986355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.