Evidence map›Paper›PMID 31964240›Full record

ArticleMolecular pain

Anxiolytic effects of polydatin through the blockade of neuroinflammation in a chronic pain mouse model.

Shao-Yu Guan, Kun Zhang, Xin-Shang Wang, Le Yang, Bin Feng, Dan-Dan Tian, Mei-Rong Gao, Shui-Bing Liu, An Liu, Ming-Gao Zhao

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  15. Temporomandibular inflammation mobilizes parvalbumin and FosB/deltaFosB neurons of amygdala and dorsal raphe.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shao-Yu GuanDepartment of Pharmacy, Precision Pharmacy and Drug Development Center, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Kun ZhangDepartment of Pharmacy, Precision Pharmacy and Drug Development Center, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Xin-Shang WangKey Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China.
Le YangDepartment of Pharmacy, Precision Pharmacy and Drug Development Center, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Bin FengDepartment of Pharmacy, School of Stomatology, Fourth Military Medical University, Xi'an, China.
Dan-Dan TianDepartment of Acupuncture-Moxibustion-Massage, Shaanxi University of Chinese Medicine, Xianyang, China.
Mei-Rong GaoDepartment of Acupuncture-Moxibustion-Massage, Shaanxi University of Chinese Medicine, Xianyang, China.
Shui-Bing LiuKey Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China.
An LiuDepartment of Pharmacy, Precision Pharmacy and Drug Development Center, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Ming-Gao ZhaoDepartment of Pharmacy, Precision Pharmacy and Drug Development Center, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.ORCID 0000-0002-7539-3887
Air Force Medical University · CNShaanxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Anxiety AgentsAnxietyChronic PainCytokinesDisease Models, AnimalDrugs, Chinese HerbalFallopia japonicaFreund's AdjuvantGlucosidesI-kappa B KinaseInflammationMaleMaze LearningMiceMice, Inbred C57BLAnti-Anxiety AgentsCytokinesDrugs, Chinese HerbalFreund's AdjuvantGlucosidesI-kappa B KinaseNF-kappa B p50 SubunitNfkb1 protein, mousepolydatinReceptors, AMPAReceptors, N-Methyl-D-AspartateStilbenesamygdalaanxietychronic paininflammationPolydatin

Identifiers

PMID31964240
PMCPMC6977205
OpenAlexW3002306283

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.