Evidence map›Paper›PMID 31964221›Full record

ArticleNeuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition2021

Age differences in neural activity related to mentalizing during person perception.

Brittany S Cassidy, Colleen Hughes, Anne C Krendl

Open access · greenAbstract read
In one paragraph

Article in Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Individualized Mapping of Functional Brain Networks in Older Adulthood.bioRxiv : the preprint server for biology · 2026
    Article
  3. Disentangling the role of executive function and episodic memory in older adults' performance on dynamic theory of mind tasks.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Age Differences in Mental State Inference of Sarcasm: Contributions of Facial Emotion Recognition and Cognitive Performance.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Aging is associated with maladaptive episodic memory-guided social decision-making.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Brittany S CassidyDepartment of Psychology, University of North Carolina , Greensboro, USA.ORCID 0000-0002-1449-0886
Colleen HughesDepartment of Psychological and Brain Sciences, Indiana University , Bloomington, USA.
Anne C KrendlDepartment of Psychological and Brain Sciences, Indiana University , Bloomington, USA.
Indiana University Bloomington · USUniversity of North Carolina at Greensboro · US

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Translating Measures of Visual Experience to Children with Autism and Down SyndromeKL2TR002530 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI ROBB, SHERI L · 2018 to 2022
$4.8M
Training in Clinical Translational Science: Maximizing the Public Health ImpactT32MH103213 · NIMH · TRUSTEES OF INDIANA UNIVERSITY · PI WILLIAM P HETRICK · 2015 to 2026
$3.4M
NCATS NIH HHS KL2 TR002530NCATS NIH HHS UL1 TR002529NIMH NIH HHS T32 MH103213
6 · The paper itself

Abstract

Mentalizing, or thinking about others' mental states, shapes social interactions. Older adults (OA) have reduced mentalizing capacities reflected by lower medial prefrontal cortex (mPFC) activation. The current study assessed if OA' lower mPFC activation reflects less spontaneous mentalizing during person perception. Younger adults (YA) and OA viewed ingroup White and outgroup Black and Asian faces and completed a mentalizing task during fMRI. Afterward, they completed a task in which they inferred mental states from faces. Using an mPFC region defined by the mentalizing task, OA had lower activity than YA during person perception. OA' mPFC activity toward faces positively related to their mentalizing outside the scanner. The extent of OA' lower mPFC activation during person perception may depend on their actual detection of mental states in faces. Further, YA', but not OA', mPFC activity distinguished between outgroups. OA' lower mentalizing-related mPFC activity may reduce their ability to individuate outgroup members.

Indexed as

AdolescentAdultAgedAged, 80 and overAgingFacial RecognitionFemaleFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleMentalizationMiddle AgedPrefrontal CortexRacial GroupsYoung Adultmedial prefrontal cortexMentalizingperson perceptionrace

Identifiers

PMID31964221
PMCPMC7371506
OpenAlexW3001729201

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.