Evidence map›Paper›PMID 31963899›Full record

ReviewNutrients2020

Regulation of Skeletal Muscle Function by Amino Acids.

Yasutomi Kamei, Yukino Hatazawa, Ran Uchitomi, Ryoji Yoshimura, Shinji Miura

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 2 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 2 syntheses or guidelines pooled it, 242 citations in OpenAlex.

  1. Pooled it
  2. Understanding the gut microbiota and sarcopenia: a systematic review.Journal of cachexia, sarcopenia and muscle · 2021
    Pooled it
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79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yasutomi KameiGraduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.
Yukino HatazawaGraduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.
Ran UchitomiGraduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.
Ryoji YoshimuraGraduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.
Shinji MiuraGraduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.ORCID 0000-0001-8806-9763
Kyoto Prefectural University · JPUniversity of Shizuoka · JP

Funding

Japanese Ministry of Education, Culture, Sports, Science, and Technology (MEXT, Tokyo) 19H04058
6 · The paper itself

Abstract

Amino acids are components of proteins that also exist free-form in the body; their functions can be divided into (1) nutritional, (2) sensory, and (3) biological regulatory roles. The skeletal muscle, which is the largest organ in the human body, representing ~40% of the total body weight, plays important roles in exercise, energy expenditure, and glucose/amino acid usage-processes that are modulated by various amino acids and their metabolites. In this review, we address the metabolism and function of amino acids in the skeletal muscle. The expression of PGC1

Indexed as

Energy MetabolismMuscle DevelopmentAmino AcidsAnimalsDietary ProteinsDietary SupplementsHumansMechanistic Target of Rapamycin Complex 1Muscle, SkeletalPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaSignal TransductionAmino AcidsDietary ProteinsMechanistic Target of Rapamycin Complex 1Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPARGC1A protein, humanamino acidbranched-chain amino acid (BCAA)energy expenditureexerciseleucinemetabolic diseasesPGC1αskeletal muscleβ-aminoisobutyric acid (BAIBA)β-hydroxy-β-methylbutyrate (HMB)

Identifiers

PMID31963899
PMCPMC7019684
OpenAlexW3000509728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.