Evidence map›Paper›PMID 31963843›Full record

ArticleMolecules (Basel, Switzerland)2020

Identification and Repurposing of Trisubstituted Harmine Derivatives as Novel Inhibitors of

Elise Pierson, Marie Haufroid, Tannu Priya Gosain, Pankaj Chopra, Ramandeep Singh, Johan Wouters

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Elise PiersonLaboratoire de Chimie Biologique Structurale (CBS), Namur Medicine and Drug Innovation Center (NAMEDIC), Namur Research Institute for Life Sciences (NARILIS), University of Namur (UNamur), B-5000 Namur, Belgium.ORCID 0000-0003-4647-3404
Marie HaufroidLaboratoire de Chimie Biologique Structurale (CBS), Namur Medicine and Drug Innovation Center (NAMEDIC), Namur Research Institute for Life Sciences (NARILIS), University of Namur (UNamur), B-5000 Namur, Belgium.ORCID 0000-0002-2816-992X
Tannu Priya GosainTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad 121001, Haryana, India.
Pankaj ChopraTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad 121001, Haryana, India.
Ramandeep SinghTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad 121001, Haryana, India.
Johan WoutersLaboratoire de Chimie Biologique Structurale (CBS), Namur Medicine and Drug Innovation Center (NAMEDIC), Namur Research Institute for Life Sciences (NARILIS), University of Namur (UNamur), B-5000 Namur, Belgium.
Translational Health Science and Technology Institute · INUniversity of Namur · BE

Funding

NIAID NIH HHS HHSN272201700059C
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug RepositioningAntitubercular AgentsDrug Evaluation, PreclinicalEnzyme InhibitorsHarmineKineticsMicrobial Sensitivity TestsMolecular Docking SimulationMycobacterium tuberculosisPhosphoric Monoester HydrolasesThermodynamicsAntitubercular AgentsEnzyme InhibitorsHarminePhosphoric Monoester Hydrolasesphosphoserine phosphatase2,7,9-trisubstituted harmine derivativesM. tuberculosisphosphoserine phosphataseSerB2

Identifiers

PMID31963843
PMCPMC7024313
OpenAlexW3000369295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.