Evidence map›Paper›PMID 31963732›Full record

ArticleMarine drugs2020

Antifouling Napyradiomycins from Marine-Derived Actinomycetes

Florbela Pereira, Joana R Almeida, Marisa Paulino, Inês R Grilo, Helena Macedo, Isabel Cunha, Rita G Sobral, Vitor Vasconcelos, Susana P Gaudêncio

Abstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  18. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Florbela PereiraLAQV, Chemistry Department, Faculty for Sciences and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal.ORCID 0000-0003-4392-4644
Joana R AlmeidaCIIMAR/CIMAR-Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, 4450-208 Matosinhos, Portugal.ORCID 0000-0001-9356-7265
Marisa PaulinoUCIBIO, Chemistry Department, Blue Biotechnology and Biomedicine Lab, Faculty for Sciences and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal.
Inês R GriloUCIBIO, Life Sciences Department, MOLMICRO of Bacterial Pathogens Lab, Faculty for Sciences and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal.
Helena MacedoUCIBIO, Chemistry Department, Blue Biotechnology and Biomedicine Lab, Faculty for Sciences and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal.
Isabel CunhaCIIMAR/CIMAR-Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, 4450-208 Matosinhos, Portugal.ORCID 0000-0002-6149-9840
Rita G SobralUCIBIO, Life Sciences Department, MOLMICRO of Bacterial Pathogens Lab, Faculty for Sciences and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal.ORCID 0000-0003-4533-7531
Vitor VasconcelosCIIMAR/CIMAR-Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, 4450-208 Matosinhos, Portugal.ORCID 0000-0003-3585-2417
Susana P GaudêncioLAQV, Chemistry Department, Faculty for Sciences and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal.ORCID 0000-0002-5510-1170

Funding

Fundação para a Ciência e a Tecnologia PTDC/QUI-QUI/119116/2010, IF/00700/2014, SFRH/BI/52130/2013, SFRH/BPD/110020/2015, PTDC/BIA-MIC/31645/2017, PTDC/BTA-GES/32359/2017, PTDC/BTA-BTA/31422/2017Fundação para a Ciência e a Tecnologia UID/Multi/04378/2019
6 · The paper itself

Abstract

The undesired attachment of micro and macroorganisms on water-immersed surfaces, known as marine biofouling, results in severe prevention and maintenance costs (billions €/year) for aquaculture, shipping and other industries that rely on coastal and off-shore infrastructures. To date, there are no sustainable, cost-effective and environmentally safe solutions to address this challenging phenomenon. Therefore, we investigated the antifouling activity of napyradiomycin derivatives that were isolated from actinomycetes from ocean sediments collected off the Madeira Archipelago. Our results revealed that napyradiomycins inhibited ≥80% of the marine biofilm-forming bacteria assayed, as well as the settlement of

Indexed as

ActinobacteriaAnimalsAquacultureBiofilmsBiofoulingDisinfectantsLarvaMytilusNaphthoquinonesStreptomycesDisinfectantsNaphthoquinonesactinomycetesantibiofilmantifoulingbiofoulingbioprospectiondrug discoveryhybrid isoprenoidsmarine natural productsmeroterpenoidsnapyradiomycins

Identifiers

PMID31963732
PMCPMC7024211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.