ReviewMolecules (Basel, Switzerland)2020
Chiral Thioureas-Preparation and Significance in Asymmetric Synthesis and Medicinal Chemistry.
Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed.
- Enantiomer-Resolved Biological Profiling and Chiral Developability Assessment of Novel Naphthylethyl Thioureas.Pharmaceutics · 2026Article
- Novel Phenethylamine-Based Aroyl Thiourea Derivatives: Design, Synthesis, and Multibiological Evaluation.ACS omega · 2026Article
- Pd(II)-Prolinate Prolinium and Pd(II)-LysGly Complexes Catalyzed the Enantioselective Aldol, Morita-Baylis-Hillman and Heck Reactions.Molecules (Basel, Switzerland) · 2026Article
- Rongalite addition to dienones: diastereoselectivity in cyclic sulfone synthesis; stereochemical rationalization and prospects as a general conjugate nucleophile.Beilstein journal of organic chemistry · 2026Article
- Design, Synthesis, and Evaluation of Voltage-gated Sodium Channel Inhibitors as Anticonvulsant Agents.Current neurovascular research · 2026Article
- Selection of Effective Moss Control Agents forPlants (Basel, Switzerland) · 2025Article
- Novel Thiourea Ligands-Synthesis, Characterization and Preliminary Study on Their Coordination Abilities.Molecules (Basel, Switzerland) · 2024Article
- Dehydroabietane-type bifunctional organocatalysts in asymmetric synthesis: recent progress.RSC advances · 2023Review
- Syntheses and structural characterization of divalent metal complexes (Co, Ni, Pd and Zn) of sterically hindered thiourea ligand and a theoretical insight of their interaction with SARS-CoV-2 enzyme.Journal of molecular structure · 2023Article
- Unravelling Structural Dynamics, Supramolecular Behavior, and Chiroptical Properties of Enantiomerically Pure Macrocyclic Tertiary Ureas and Thioureas.The Journal of organic chemistry · 2023Article
- Bis-Thiourea Chiral Sensor for the NMR Enantiodiscrimination ofThe Journal of organic chemistry · 2022Article
- Mononuclear Tricoordinate Copper(I) and Silver(I) Halide Complexes of a Sterically Bulky Thiourea Ligand and a Computational Insight of Their Interaction with Human Insulin.Molecules (Basel, Switzerland) · 2022Article
- Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives.Molecules (Basel, Switzerland) · 2022Review
- Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis.RSC medicinal chemistry · 2021Review
- Novel Selenoureas Based onMaterials (Basel, Switzerland) · 2021Article
- A more sustainable isothiocyanate synthesis by amine catalyzed sulfurization of isocyanides with elemental sulfur.RSC advances · 2021Article
- The Impact of Solvent and the Receptor Structure on Chiral Recognition Using Model Acyclic Bisamides Decorated with Glucosamine Pendant Arms.The Journal of organic chemistry · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
For almost 20 years, thioureas have been experiencing a renaissance of interest with the emerged development of asymmetric organocatalysts. Due to their relatively high acidity and strong hydrogen bond donor capability, they differ significantly from ureas and offer, appropriately modified, great potential as organocatalysts, chelators, drug candidates, etc. The review focuses on the family of chiral thioureas, presenting an overview of the current state of knowledge on their synthesis and selected applications in stereoselective synthesis and drug development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.