Evidence map›Paper›PMID 31963662›Full record

ArticleInternational journal of molecular sciences2020

Transcriptome Modifications in the Porcine Intramuscular Adipocytes during Differentiation and Exogenous Stimulation with TNF-α and Serotonin.

Asuka Tada, Md Aminul Islam, Akm Humayun Kober, Kohtaro Fukuyama, Michihiro Takagi, Manami Igata, Leonardo Albarracin, Wakako Ikeda-Ohtsubo, Kenji Miyazawa, Kazutoyo Yoda and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Effect ofAquaculture nutrition · 2024
    Article
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  7. Animals : an open access journal from MDPI · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Serotonin in Health and Disease.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Asuka TadaFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.
Md Aminul IslamFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.ORCID 0000-0003-1979-9652
Akm Humayun KoberFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.
Kohtaro FukuyamaFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.
Michihiro TakagiFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.
Manami IgataFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.
Leonardo AlbarracinFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.ORCID 0000-0001-8216-2190
Wakako Ikeda-OhtsuboFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.
Kenji MiyazawaTechnical Research Laboratory, Takanashi Milk Products Co., Ltd., Yokohama Kanagawa, Yokohama 241-0023, Japan.
Kazutoyo YodaTechnical Research Laboratory, Takanashi Milk Products Co., Ltd., Yokohama Kanagawa, Yokohama 241-0023, Japan.
Fang HeTechnical Research Laboratory, Takanashi Milk Products Co., Ltd., Yokohama Kanagawa, Yokohama 241-0023, Japan.
Hideki TakahashiLaboratory of Plant Pathology, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.ORCID 0000-0001-5398-1867
Julio VillenaFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.ORCID 0000-0003-4941-4960
Hisashi AsoLivestock Immunology Unit, International Education and Research Center for Food Agricultural Immunology (CFAI), Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.
Haruki KitazawaFood and Feed Immunology Group, Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.
Tohoku University · JPMegmilk Snow Brand (Japan) · JPConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

Japan Society for the Promotion of Science (A) (19H00965); (B) (16H05019); (26660216, 16K15028); 18F18081 and 15F15401Ministry of Education, Culture, Sports, Science and Technology 16H06429, 16K21723, and 16H06435
6 · The paper itself

Abstract

Adipocytes are dynamic cells that have critical functions to maintain body energy homeostasis. Adipocyte physiology is affected by the adipogenic differentiation, cell program, as well as by the exogenous stimulation of biochemical factors, such as serotonin and TNF-α. In this work, we investigated the global transcriptome modifications when porcine intramuscular preadipocyte (PIP) was differentiated into porcine mature adipocyte (pMA). Moreover, we studied transcriptome changes in pMA after stimulation with serotonin or TNF-α by using a microarray approach. Transcriptome analysis revealed that the expression of 270, 261, and 249 genes were modified after differentiation, or after serotonin and TNF-α stimulation, respectively. Expression changes in

Indexed as

AdipocytesAnimalsCell DifferentiationCells, CulturedDose-Response Relationship, DrugFemaleGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksLipid MetabolismMuscle, SkeletalSerotoninSwineTumor Necrosis Factor-alphaSerotoninTumor Necrosis Factor-alphaadipogenesisporcine intramuscular preadipocyte (PIP)porcine mature adipocyte (pMA)serotoninserotonin receptorTNF-αtranscriptome

Identifiers

PMID31963662
PMCPMC7013444
OpenAlexW2998964670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.