Evidence map›Paper›PMID 31963650›Full record

ArticleJournal of clinical medicine2020

The Effect of Proton Pump Inhibitor Use on Renal Function in Kidney Transplanted Patients.

Dominik J G Flothow, Barbara Suwelack, Hermann Pavenstädt, Katharina Schütte-Nütgen, Stefan Reuter

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Long-term Effects of Gastric Acid Prophylaxis in Kidney Transplant Recipients.Revista de nefrologia, dialisis y transplante : publicacion conjunta de la Asociacion Regional de Dialisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires y la Sociedad Argentina de Nefrologia
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dominik J G FlothowDepartment of Medicine D, University Hospital of Muenster, 48149 Münster, Germany.
Barbara SuwelackDepartment of Medicine D, University Hospital of Muenster, 48149 Münster, Germany.
Hermann PavenstädtDepartment of Medicine D, University Hospital of Muenster, 48149 Münster, Germany.
Katharina Schütte-NütgenDepartment of Medicine D, University Hospital of Muenster, 48149 Münster, Germany.
Stefan ReuterDepartment of Medicine D, University Hospital of Muenster, 48149 Münster, Germany.ORCID 0000-0001-6345-6206
University Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, proton pump inhibitor (PPI) intake has been linked to acute kidney injury and chronic kidney disease. The objective of this study was to assess the effect of PPIs on renal function and rejection rate in kidney transplant patients. We performed a single center, retrospective analysis of 455 patients who received a kidney transplant between May 2010 and July 2015. Median follow-up time was 3.3 years. PPI prescription was assessed in half-year intervals. Primary outcome parameters were the estimated glomerular filtration rate (eGFR), change in the eGFR, and >30% and >50% eGFR decline for different time periods (up to four years post-transplantation). Our secondary outcome parameter was occurrence of biopsy proven acute rejection (BPAR) in the first two years after transplantation. Except for >30% eGFR decline from half a year to two years post-transplantation (

Indexed as

GFRkidney transplantationproton pump inhibitortransplant rejection

Identifiers

PMID31963650
PMCPMC7019820
OpenAlexW2999936376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.