ArticleLife (Basel, Switzerland)2020
Life in The Context of Order and Complexity.
Article in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Periodic Temperature Fluctuations as an Energy Source for RNA Evolution.Life (Basel, Switzerland) · 2026Article
- Molecular Complexity Constrained Early Amino Acid Recruitment into the Genetic Code.Genome biology and evolution · 2026Article
- Entropy Production in Epithelial Monolayers Due to Collective Cell Migration.Entropy (Basel, Switzerland) · 2025Review
- The GARD Prebiotic Reproduction Model Described in Order and Complexity.Life (Basel, Switzerland) · 2024Article
- High mirror symmetry in mouse exploratory behavior.Frontiers in behavioral neuroscience · 2024Article
- Order and Complexity in the RNA World.Life (Basel, Switzerland) · 2023Article
- Monitoring the advancements in the technology of artificial cells by determining their complexity degree: Hints from complex systems descriptors.Frontiers in bioengineering and biotechnology · 2023Article
- Spontaneous Formation of Functional Structures in Messy Environments.Life (Basel, Switzerland) · 2022Article
- Molecules, Information and the Origin of Life: What Is Next?Molecules (Basel, Switzerland) · 2021Article
- Shock Processing of Amino Acids Leading to Complex Structures-Implications to the Origin of Life.Molecules (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is generally accepted that life requires structural complexity. However, a chaotic mixture of organic compounds like the one formed by extensive reaction sequences over time may be extremely complex, but could just represent a static asphalt-like dead end situation. Likewise, it is accepted that life requires a certain degree of structural order. However, even extremely ordered structures like mineral crystals show no tendency to be alive. So neither complexity nor order alone can characterize a living organism. In order to come close to life, and in order for life to develop to higher organisms, both conditions have to be fulfilled and advanced simultaneously. Only a combination of the two requirements, complexity and structural order, can mark the difference between living and dead matter. It is essential for the development of prebiotic chemistry into life and characterizes the course and the result of Darwinian evolution. For this reason, it is worthwhile to define complexity and order as an essential pair of characteristics of life and to use them as fundamental parameters to evaluate early steps in prebiotic development. A combination of high order and high complexity also represents a universal type of biosignature which could be used to identify unknown forms of life or remnants thereof.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.