Evidence map›Paper›PMID 31963577›Full record

ArticleInternational journal of environmental research and public health2020

Serum Levels of Commonly Detected Persistent Organic Pollutants and Per- and Polyfluoroalkyl Substances (PFASs) and Mammographic Density in Postmenopausal Women.

Eunjung Lee, April Kinninger, Giske Ursin, Chiuchen Tseng, Susan Hurley, Miaomiao Wang, Yunzhu Wang, June-Soo Park, Myrto Petreas, Dennis Deapen and 1 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eunjung LeeDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
April KinningerDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Giske UrsinCancer Registry of Norway, 0304 Oslo, Norway.
Chiuchen TsengDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Susan HurleyDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94704, USA.
Miaomiao WangEnvironmental Chemistry Laboratory, Department of Toxic Substances Control, Berkeley, CA 94710, USA.
Yunzhu WangEnvironmental Chemistry Laboratory, Department of Toxic Substances Control, Berkeley, CA 94710, USA.
June-Soo ParkEnvironmental Chemistry Laboratory, Department of Toxic Substances Control, Berkeley, CA 94710, USA.
Myrto PetreasEnvironmental Chemistry Laboratory, Department of Toxic Substances Control, Berkeley, CA 94710, USA.
Dennis DeapenDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Peggy ReynoldsDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94704, USA.

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9M
Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI XIWEI WU · 1985 to 2026
$86.3M
Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
CALIFORNIA TEACHERS STUDYR01CA077398 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BERNSTEIN, LESLIE · 1998 to 2014
$29.7M
Oil and Gas as Drivers of Climate Change and Health: Developing unique resources to investigate multi-level and diverse effects of exposure to oil and gas wellsU01CA199277 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI LACEY, JAMES V, MARTINEZ, MARIA ELENA · 2015 to 2024
$20.7M
New Biospecimens to Enhance Research in the California Teachers Study CohortUM1CA164917 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI LACEY, JAMES V · 2012 to 2015
$10.1M
NCI NIH HHS P30-CA023100NCI NIH HHS P30-CA033572NCI NIH HHS R01-CA077398NCI NIH HHS U01-CA199277NCI NIH HHS UM1-CA164917NIEHS NIH HHS P30 ES007048
6 · The paper itself

Abstract

There are little epidemiological data on the impact of persistent organic pollutants (POPs) and endocrine disruptors on mammographic density (MD), a strong predictor of breast cancer. We assessed MD in 116 non-Hispanic white post-menopausal women for whom serum concentrations of 23 commonly detected chemicals including 3 polybrominated diphenyl ethers (PBDEs), 8 per- and polyfluoroalkyl substances (PFASs), and 12 polychlorinated biphenyls (PCBs) had been measured. Linear regression analyses adjusting for potential confounders were used to examine the associations between the levels of the chemical compounds, modeled as continuous and dichotomized (above/below median) variables, and square-root-transformed MD. None of the associations were statistically significant after correcting for multiple testing. Prior to correction for multiple testing, all chemicals with un-corrected

Indexed as

Breast DensityPostmenopauseAgedCaliforniaEnvironmental PollutantsFemaleFluorocarbonsHalogenated Diphenyl EthersHumansMiddle AgedEnvironmental PollutantsFluorocarbonsHalogenated Diphenyl Ethersmammographic densityper- and polyfluoroalkyl substancespersistent organic pollutantspolybrominated diphenyl etherspolychlorinated biphenyls

Identifiers

PMID31963577
PMCPMC7013395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.