Evidence map›Paper›PMID 31963487›Full record

ReviewMicroorganisms2020

Warding Off Recurrent Yeast and Bacterial Vaginal Infections: Lactoferrin and Lactobacilli.

Fabiana Superti, Francesco De Seta

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05122065 (Defining the Vaginal Microbiome and the Vaginal pH of Menopausal Women With and Without Genitourinary Syndrome and With and Without Hormone Replacement Therapy), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05122065 unknown statusnot on this mapstarted 2021, after this paper: background citation

Defining the Vaginal Microbiome and the Vaginal pH of Menopausal Women With and Without Genitourinary Syndrome and With and Without Hormone Replacement Therapy

TypeobservationalSponsorFemTec Health Inc.Ran2021 to 2022Enrolled432ConditionsMenopause, Hormone Replacement Therapy, Genitourinary Syndrome of Menopause
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Prophylactic Potential ofMicroorganisms · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Candida albicans: the current status regarding vaginal infections.Applied microbiology and biotechnology · 2025
    Review
  8. Synergistic Inhibition ofPathogens (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. InstantMicromachines · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The Lactoferrin Phenomenon-A Miracle Molecule.Molecules (Basel, Switzerland) · 2022
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Fabiana SupertiNational Centre for Innovative Technologies in Public Health, National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy.ORCID 0000-0003-4909-7598
Francesco De SetaInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", University of Trieste, via dell'Istria 65/1, 34137 Trieste, Italy.
Istituto Superiore di Sanità · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaginal infections are the most prevalent women's health problem. Incompetent diagnosis, inappropriate treatments, and antibiotic resistance are the main causes of the unsatisfactory results of conventional, antimicrobic treatment for these infections. Research has thus been conducted to identify new treatments for these genital diseases. The significant enhancement in our knowledge of vaginal microbiota has permitted the development of new, nonpharmacological strategies for the treatment of vaginal infections that seek to restore the balance of vaginal microflora, as opposed to modifying its components. Among these approaches, bioactive compounds, such as probiotics and nutraceutical proteins (such as lactoferrin), deserve particular attention. The aim of this review is to examine the role of probiotics (mainly

Indexed as

aerobic vaginitisbacterial vaginosisLactobacilluslactoferrinsafetyvulvovaginal candidiasis

Identifiers

PMID31963487
PMCPMC7023241
OpenAlexW3000097417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.