Evidence map›Paper›PMID 31963449›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Indocyanine Green-Nexturastat A-PLGA Nanoparticles Combine Photothermal and Epigenetic Therapy for Melanoma.

Debbie K Ledezma, Preethi B Balakrishnan, Juliana Cano-Mejia, Elizabeth E Sweeney, Melissa Hadley, Catherine M Bollard, Alejandro Villagra, Rohan Fernandes

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  12. Article
  13. Moving Forward in Nano-Immune Interactions.Nanomaterials (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Immune Responses to Nanomaterials for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2021
    Article
  16. Solutions to the Drawbacks of Photothermal and Photodynamic Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  17. Photothermal therapies to improve immune checkpoint blockade for cancer.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2020
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Debbie K LedezmaThe Institute for Biomedical Sciences, The George Washington University, 2300 Eye Street NW, Room 561, Washington, DC 20037, USA.ORCID 0000-0001-7922-3773
Preethi B BalakrishnanThe George Washington Cancer Center, The George Washington University, 800 22nd St NW, Science and Engineering Hall, Suite 8000, Washington, DC 20052, USA.ORCID 0000-0001-5576-7530
Juliana Cano-MejiaThe George Washington Cancer Center, The George Washington University, 800 22nd St NW, Science and Engineering Hall, Suite 8000, Washington, DC 20052, USA.
Elizabeth E SweeneyThe George Washington Cancer Center, The George Washington University, 800 22nd St NW, Science and Engineering Hall, Suite 8000, Washington, DC 20052, USA.
Melissa HadleyThe George Washington Cancer Center, The George Washington University, 800 22nd St NW, Science and Engineering Hall, Suite 8000, Washington, DC 20052, USA.
Catherine M BollardThe Institute for Biomedical Sciences, The George Washington University, 2300 Eye Street NW, Room 561, Washington, DC 20037, USA.
Alejandro VillagraThe George Washington Cancer Center, The George Washington University, 800 22nd St NW, Science and Engineering Hall, Suite 8000, Washington, DC 20052, USA.ORCID 0000-0001-9346-8355
Rohan FernandesThe Institute for Biomedical Sciences, The George Washington University, 2300 Eye Street NW, Room 561, Washington, DC 20037, USA.ORCID 0000-0001-9439-4626
George Washington University · USChildren's National · US

Funding

Engineered Ensemble Nanoimmunotherapies for CancerR37CA226171 · NCI · GEORGE WASHINGTON UNIVERSITY · PI FERNANDES, ROHAN · 2019 to 2024
$2.6M
BSquared Consulting Group NANCI NIH HHS R37 CA226171NCI NIH HHS R37CA226171The George Washington Cancer Center NA
6 · The paper itself

Abstract

In this study, we describe poly (lactic-

Indexed as

epigenetic therapyHDAC inhibitorsindocyanine greenmelanomaNexturastat Aphotothermal therapyPLGA nanoparticles

Identifiers

PMID31963449
PMCPMC7022377
OpenAlexW2999487647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.