Evidence map›Paper›PMID 31963394›Full record

ArticleCancers2020

Mutation Status and Epithelial Differentiation Stratify Recurrence Risk in Chordoid Meningioma-A Multicenter Study with High Prognostic Relevance.

Maria-Magdalena Georgescu, Anil Nanda, Yan Li, Bret C Mobley, Phyllis L Faust, Jack M Raisanen, Adriana Olar

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Brain Invasion and Trends in Molecular Research on Meningioma.Brain tumor research and treatment · 2023
    Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Maria-Magdalena GeorgescuDepartment of Pathology, Louisiana State University, Shreveport, LA 71103, USA.
Anil NandaDepartment of Neurosurgery, Rutgers University, Camden, NJ 08901, USA.
Yan LiDepartment of Pathology, Louisiana State University, Shreveport, LA 71103, USA.
Bret C MobleyDepartment of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Phyllis L FaustDepartment of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA.
Jack M RaisanenDepartment of Pathology, the University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Adriana OlarDepartment of Pathology and Laboratory Medicine and Neurosurgery, Medical University of South Carolina and Hollings Cancer Center, Charleston, SC 29425, USA.
Louisiana State University in Shreveport · USColumbia University · USMUSC Hollings Cancer Center · USRutgers, The State University of New Jersey · USThe University of Texas Southwestern Medical Center · USVanderbilt University Medical Center · US

Funding

CSRD VA 1
6 · The paper itself

Abstract

Chordoid meningioma is a rare WHO grade II histologic variant. Its molecular alterations or their impact on patient risk stratification have not been fully explored. We performed a multicenter, clinical, histological, and genomic analysis of chordoid meningiomas from 30 patients (34 tumors), representing the largest integrated study to date. By NHERF1 microlumen immunohistochemical detection, three epithelial differentiation (ED) groups emerged: #1/fibroblastic-like, #2/epithelial-poorly-differentiated and #3/epithelial-well-differentiated. These ED groups correlated with tumor location and genetic profiling, with

Indexed as

ATMchordoid meningiomachromatin remodeling genesepithelial differentiationNF2NHERF1/EBP50TRAF7

Identifiers

PMID31963394
PMCPMC7016786
OpenAlexW2998897391

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.