Evidence map›Paper›PMID 31963158›Full record

ArticleInternational journal of molecular sciences2020

Proteomics-Based Evidence for a Pro-Oncogenic Role of ESRP1 in Human Colorectal Cancer Cells.

Ugo Ala, Marta Manco, Giorgia Mandili, Emanuela Tolosano, Francesco Novelli, Paolo Provero, Fiorella Altruda, Sharmila Fagoonee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Molecular and Translational Research on Colorectal Cancer.International journal of molecular sciences · 2020
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ugo AlaDepartment of Veterinary Science, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-5408-6397
Marta MancoMolecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, 10126 Turin, Italy.
Giorgia MandiliCenter for Experimental Research and Medical Studies, Azienda Universitaria Ospedaliera Città della Salute e della Scienza, 10126 Turin, Italy.
Emanuela TolosanoMolecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-1622-2340
Francesco NovelliCenter for Experimental Research and Medical Studies, Azienda Universitaria Ospedaliera Città della Salute e della Scienza, 10126 Turin, Italy.
Paolo ProveroMolecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, 10126 Turin, Italy.
Fiorella AltrudaMolecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-6238-1860
Sharmila FagooneeInstitute of Biostructure and Bioimaging, CNR c/o Molecular Biotechnology Centre, 10126 Turin, Italy.ORCID 0000-0001-6070-6716
University of Turin · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITInstitute of Biostructure and Bioimaging · ITVita-Salute San Raffaele University · IT

Funding

Associazione Italiana Ricerca sul Cancro 5 × mille no. 12182, IG no. 15257IRMI Italian Regenerative Medicine Infrastructure program (Italian Ministry of Health) CTN01 00177 88744Italian Ministry of Health-Progetti Ricerca Finalizzata RF-2013-02354892
6 · The paper itself

Abstract

The RNA-binding protein, Epithelial Splicing Regulatory Protein 1 (ESRP1) can promote or suppress tumorigenesis depending on the cell type and disease context. In colorectal cancer, we have previously shown that aberrantly high ESRP1 expression can drive tumor progression. In order to unveil the mechanisms by which ESRP1 can modulate cancer traits, we searched for proteins affected by modulation of

Indexed as

Cell CycleCell Line, TumorColorectal NeoplasmsComputational BiologyGene Expression Regulation, NeoplasticHumansProtein BindingProteomicsRNA-Binding ProteinsESRP1 protein, humanRNA-Binding Proteinsbioinformaticscolorectal cancerESRP1proteomics

Identifiers

PMID31963158
PMCPMC7014300
OpenAlexW3000082254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.