Evidence map›Paper›PMID 31962289›Full record

ArticleAddictive behaviors2020

Contextual risk among adolescents receiving opioid prescriptions for acute pain in pediatric ambulatory care settings.

Genevieve F Dash, Sarah W Feldstein Ewing, Corrin Murphy, Karen A Hudson, Anna C Wilson

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Genevieve F DashDepartment of Psychological Sciences, University of Missouri-Columbia, 210 McAlester Hall, Columbia, MO 65211, USA. Electronic address: genevievedash@mail.missouri.edu.
Sarah W Feldstein EwingDepartment of Child & Adolescent Psychiatry, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mailstop UHN80R1, Portland, OR 97239, USA. Electronic address: feldstei@ohsu.edu.
Corrin MurphyDepartment of Pediatrics, Institute on Development and Disability, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mailstop CDRC, Portland, OR 97239, USA. Electronic address: murphcor@ohsu.edu.
Karen A HudsonDepartment of Child & Adolescent Psychiatry, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mailstop UHN80R1, Portland, OR 97239, USA. Electronic address: hudsonk@ohsu.edu.
Anna C WilsonDepartment of Pediatrics, Institute on Development and Disability, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mailstop CDRC, Portland, OR 97239, USA. Electronic address: longann@ohsu.edu.
Oregon Health & Science University · USUniversity of Missouri · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Psychology of Alcohol Use and Dependence TrainingT32AA013526 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI DENIS M MCCARTHY, KENNETH JAMES SHER · 2002 to 2026
$9.0M
Risk for opioid abuse and misuse in adolescenceR01DA044778 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI FELDSTEIN EWING, SARAH W., WILSON, ANNA CAMILLE · 2018 to 2022
$3.4M
Deriving a de novo adolescent addiction treatment from developmental brain dataK24AA026876 · NIAAA · UNIVERSITY OF RHODE ISLAND · PI Sarah W. Feldstein Ewing · 2018 to 2026
$1.3M
NCATS NIH HHS UL1 TR002369NIAAA NIH HHS K24 AA026876NIAAA NIH HHS T32 AA013526NIDA NIH HHS R01 DA044778
6 · The paper itself

Abstract

Many adults with opioid use disorder (OUD) report that their first exposure to opioids was in the course of routine pain treatment in medical care settings. Adolescents receive opioid prescriptions with frequency, but are susceptible to a constellation of unique risks in the context of pain management. This empirical study presents the first cohort of adolescents recruited from ambulatory medical care within 72 h of their receipt of opioids to treat acute pain. The primary aim was to capture a time-sensitive report of the intersection of prescription opioid receipt and contextual risks for opioid misuse related to pain experience, mental health symptoms, and substance use at the adolescent and parental levels. Data were collected from 70 14-19-year-old adolescents and their accompanying parent. Results reflected that 90% of this sample of adolescents reported 2 or more risks and 35% reported 5 or more risks for future opioid misuse. Pain catastrophizing (46%) and alcohol use (40%) and were the most common adolescent-level risk factors; mother history of chronic pain (32%) and parent anxiety (21%) were the most common parent-level risk factors. Past-week parent pain intensity showed the strongest association with adolescent past-week pain intensity; neither was associated with adolescent OUD symptoms. Adolescent pain catastrophizing most reliably predicted OUD symptoms; parent pain interference was also associated. Seventy-one percent of parents reported keeping opioids at home, a relevant risk factor for future misuse. These findings illuminate the intersection between adolescent and parental risks in the context of pediatric opioid prescribing for acute pain management, and provide initial insight into potential points of prevention early in adolescent pain treatment, including avenues by which to inform and enhance prescriber decision-making regarding factors to be weighed in adolescent candidacy for opioid therapy.

Indexed as

Prescription Drug MisuseAcute PainAdolescentAmbulatory CareAnalgesics, OpioidFamily CharacteristicsFemaleHumansMaleOpioid-Related DisordersParentsPrescription DrugsRisk FactorsYoung AdultAnalgesics, OpioidPrescription DrugsAdolescentsFamily factorsOpioid usePainPrescription

Identifiers

PMID31962289
PMCPMC7024039
OpenAlexW3000195453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.