Evidence map›Paper›PMID 31961872›Full record

ArticlePLoS neglected tropical diseases2020

Assessing the impact of aggregating disease stage data in model predictions of human African trypanosomiasis transmission and control activities in Bandundu province (DRC).

María Soledad Castaño, Martial L Ndeffo-Mbah, Kat S Rock, Cody Palmer, Edward Knock, Erick Mwamba Miaka, Joseph M Ndung'u, Steve Torr, Paul Verlé, Simon E F Spencer and 4 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

María Soledad CastañoDepartment of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.ORCID 0000-0003-4966-2243
Martial L Ndeffo-MbahSchool of Public Health, Yale University, New Haven, Connecticut, United States of America.
Kat S RockZeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, University of Warwick, Coventry, United Kingdom.
Cody PalmerInstitute of Disease Modeling, Seattle, Washington, United States of America.
Edward KnockZeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, University of Warwick, Coventry, United Kingdom.
Erick Mwamba MiakaProgramme National de Lutte contre la Trypanosomiase Humaine Africaine, Kinshasa, the Democratic Republic of the Congo.
Joseph M Ndung'uFoundation for Innovative New Diagnostics, Geneva, Switzerland.
Steve TorrDepartment of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.ORCID 0000-0001-9550-4030
Paul VerléDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Simon E F SpencerZeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, University of Warwick, Coventry, United Kingdom.
Alison GalvaniSchool of Public Health, Yale University, New Haven, Connecticut, United States of America.
Caitlin BeverInstitute of Disease Modeling, Seattle, Washington, United States of America.
Matt J KeelingZeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, University of Warwick, Coventry, United Kingdom.
Nakul ChitnisDepartment of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.

Funding

Biotechnology and Biological Sciences Research Council BB/L019035/1
6 · The paper itself

Abstract

Since the turn of the century, the global community has made great progress towards the elimination of gambiense human African trypanosomiasis (HAT). Elimination programs, primarily relying on screening and treatment campaigns, have also created a rich database of HAT epidemiology. Mathematical models calibrated with these data can help to fill remaining gaps in our understanding of HAT transmission dynamics, including key operational research questions such as whether integrating vector control with current intervention strategies is needed to achieve HAT elimination. Here we explore, via an ensemble of models and simulation studies, how including or not disease stage data, or using more updated data sets affect model predictions of future control strategies.

Indexed as

Data ManagementDemocratic Republic of the CongoDisease EradicationHumansModels, TheoreticalOperations ResearchTrypanosomiasis, African

Identifiers

PMID31961872
PMCPMC6994134

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.