Evidence map›Paper›PMID 31961695›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2020

Magnetic Alignment of Polymer Nanodiscs Probed by Solid-State NMR Spectroscopy.

Thirupathi Ravula, JaeWoong Kim, Dong-Kuk Lee, Ayyalusamy Ramamoorthy

Open access · greenAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Magnetically aligned nanodiscs enable direct measurement ofJournal of magnetic resonance (San Diego, Calif. : 1997) · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Synthesis, Characterization, and Nanodisc Formation of Non-ionic Polymers*.Angewandte Chemie (International ed. in English) · 2021
    Article
  7. Solid-State NMR Study to Probe the Effects of Divalent Metal Ions (CaLangmuir : the ACS journal of surfaces and colloids · 2021
    Article
  8. Review
  9. Natural-abundanceChemical communications (Cambridge, England) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Thirupathi RavulaBiophysics Program and Department of Chemistry, Macromolecular Science and Engineering, Biomedical Engineering , University of Michigan , Ann Arbor , Michigan 48109-1055 , United States.
JaeWoong KimDepartment of Fine Chemistry , Seoul National University of Science and Technology , Seoul 01811 , Republic of Korea.
Dong-Kuk LeeDepartment of Fine Chemistry , Seoul National University of Science and Technology , Seoul 01811 , Republic of Korea.
Ayyalusamy RamamoorthyBiophysics Program and Department of Chemistry, Macromolecular Science and Engineering, Biomedical Engineering , University of Michigan , Ann Arbor , Michigan 48109-1055 , United States.ORCID 0000-0003-1964-1900
Seoul National University of Science and Technology · KRUniversity of Michigan · US

Funding

Supplement: Investigation of Membrane-Bound Cytochromes-P450-b5 InteractionsR01GM084018 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAMAMOORTHY, AYYALUSAMY · 2009 to 2018
$3.8M
Membrane interaction and disruption by the Alzheimer's amyloid-beta peptideR01AG048934 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAMAMOORTHY, AYYALUSAMY · 2016 to 2020
$2.0M
Development of biophysical approaches to investigate high-resolution structure and dynamics of membrane proteinsR35GM139573 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ayyalusamy Ramamoorthy · 2021 to 2026
$2.0M
NIA NIH HHS R01 AG048934NIGMS NIH HHS R01 GM084018NIGMS NIH HHS R35 GM139573
6 · The paper itself

Abstract

The ability of amphipathic polymers to self-assemble with lipids and form nanodiscs has been a boon for the field of functional reconstitution of membrane proteins. In a field dominated by detergent micelles, a unique feature of polymer nanodiscs is their much-desired ability to align in the presence of an external magnetic field. Magnetic alignment facilitates the application of solid-state nuclear magnetic resonance (NMR) spectroscopy and aids in the measurement of residual dipolar couplings via well-established solution NMR spectroscopy. In this study, we comprehensively investigate the magnetic alignment properties of styrene maleimide quaternary ammonium (SMA-QA) polymer-based nanodiscs by using

Indexed as

ChloridesDimyristoylphosphatidylcholineLipid BilayersMagnetic PhenomenaMagnetic Resonance SpectroscopyMaleimidesNanostructuresNitrogen IsotopesPhosphorusPolystyrenesQuaternary Ammonium CompoundsYtterbiumChloridesDimyristoylphosphatidylcholineLipid BilayersMaleimidesNitrogen IsotopesPhosphorusPolystyrenesQuaternary Ammonium CompoundsYtterbiumytterbium trichloride

Identifiers

PMID31961695
PMCPMC7414804
OpenAlexW3001615912

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.