Evidence map›Paper›PMID 31961652›Full record

ArticleACS infectious diseases2020

Non-anticoagulant Heparin as a Pre-exposure Prophylaxis Prevents Lyme Disease Infection.

Yi-Pin Lin, Yanlei Yu, Ashley L Marcinkiewicz, Patricia Lederman, Thomas M Hart, Fuming Zhang, Robert J Linhardt

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  3. Article
  4. Review
  5. Non-anticoagulant heparin derivatives for COVID-19 treatment.International journal of biological macromolecules · 2023
    Review
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  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yi-Pin LinDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, New York 12208, United States.ORCID 0000-0002-5240-2031
Yanlei YuDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 110 8th Street, Troy, New York 12180, United States.
Ashley L MarcinkiewiczDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, New York 12208, United States.
Patricia LedermanDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, New York 12208, United States.
Thomas M HartDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, New York 12208, United States.
Fuming ZhangDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 110 8th Street, Troy, New York 12180, United States.ORCID 0000-0003-2803-3704
Robert J LinhardtDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 110 8th Street, Troy, New York 12180, United States.ORCID 0000-0003-2219-5833
New York State Department of Health · USRensselaer Polytechnic Institute · US

Funding

The role ofglycosaminoglycan N-sulfation in glomerular biology/pathobiologyR01DK111958 · NIDDK · LOUISIANA STATE UNIV HSC SHREVEPORT · PI MCCARTHY, KEVIN JOHN · 2017 to 2021
$2.6M
NIDDK NIH HHS R01 DK111958
6 · The paper itself

Abstract

Lyme disease (LD) is caused by the spirochete

Indexed as

Pre-Exposure ProphylaxisAnimalsBorrelia burgdorferiFemaleHeparinLyme DiseaseMiceMice, Inbred BALB CHeparinBorreliaheparinLyme diseaseNACHpre-exposure prophylaxis

Identifiers

PMID31961652
PMCPMC7241291
OpenAlexW3000975943

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.