Evidence map›Paper›PMID 31961646›Full record

ArticleACS chemical neuroscience2020

Test-Retest Repeatability of [

Lara García-Varela, David Vállez García, Manuel Rodríguez-Pérez, Aren van Waarde, Jürgen W A Sijbesma, Anna Schildt, Chantal Kwizera, Pablo Aguiar, Tomás Sobrino, Rudi A J O Dierckx and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Designing a Small Molecule for PET Radiotracing: [Molecules (Basel, Switzerland) · 2025
    Review
  2. Oral Administration of [Molecular imaging and biology · 2025
    Article
  3. Article
  4. Quantification of P-glycoprotein function at the human blood-brain barrier using [European journal of nuclear medicine and molecular imaging · 2023
    Article
  5. PET imaging of animal models with depressive-like phenotypes.European journal of nuclear medicine and molecular imaging · 2023
    Review
  6. Article
  7. Molecular pharmaceutics · 2021
    Article
  8. Pharmacokinetic Modeling of [Molecular pharmaceutics · 2020
    Article
  9. PET Imaging of [Molecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lara García-VarelaDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.ORCID 0000-0001-9803-4708
David Vállez GarcíaDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.
Manuel Rodríguez-PérezClinical Neurosciences Research Laboratory , Health Research Institute of Santiago de Compostela (IDIS) , Santiago de Compostela 15706 , Spain.
Aren van WaardeDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.
Jürgen W A SijbesmaDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.
Anna SchildtDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.
Chantal KwizeraDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.
Pablo AguiarDepartment of Nuclear Medicine and Molecular Imaging Group , Clinical University Hospital, IDIS Health Research Institute , Santiago de Compostela 15706 , Spain.
Tomás SobrinoClinical Neurosciences Research Laboratory , Health Research Institute of Santiago de Compostela (IDIS) , Santiago de Compostela 15706 , Spain.
Rudi A J O DierckxDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.
Philip H ElsingaDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.
Gert LuurtsemaDepartment of Nuclear Medicine and Molecular Imaging , University of Groningen, University Medical Center Groningen , Hanzeplein 1 , P.O. Box 30001, 9713 GZ Groningen , The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In longitudinal PET studies, animals are repeatedly anesthetized which may affect the repeatability of PET measurements. The aim of this study was to assess the effect of anesthesia on the P-gp function as well as the reproducibility of [

Indexed as

Radionuclide ImagingAnimalsATP Binding Cassette Transporter, Subfamily B, Member 1Blood-Brain BarrierBrainMaleRadiopharmaceuticalsRats, WistarReproducibility of ResultsRodentiaATP Binding Cassette Transporter, Subfamily B, Member 1RadiopharmaceuticalsAnesthesiablood-brain barrierisofluraneP-glycoproteinpositron emission tomographypreclinical studiestest−retest reproducibility

Identifiers

PMID31961646
PMCPMC7034080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.