Evidence map›Paper›PMID 31961492›Full record

Observational studyArthritis care & research2021

Comparing the Patient-Reported Physical Function Outcome Measures in a Real-Life International Cohort of Patients With Psoriatic Arthritis.

Ying Ying Leung, Ana-Maria Orbai, Maarten de Wit, Andra Balanescu, Emmanuelle Dernis, Martin Soubrier, Lihi Eder, Josef S Smolen, Laura C Coates, Laure Gossec and 1 more

Open access · greenAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Arthritis care & research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 8 countries.

Ying Ying LeungSingapore General Hospital, Duke-National University of Singapore Medical School, Singapore.ORCID 0000-0001-8492-6342
Ana-Maria OrbaiJohn Hopkins University, Baltimore, Maryland.ORCID 0000-0001-8644-8567
Maarten de WitPatient Research Partner, VU Medical Center, Amsterdam, The Netherlands.ORCID 0000-0002-8428-6354
Andra BalanescuMaria Hospital, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania.
Emmanuelle DernisLe Mans Central Hospital, Le Mans, France.
Martin SoubrierGabriel Montpied Hospital, Clermont Ferrand, France.
Lihi EderWomen's College Hospital, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-1473-1715
Josef S SmolenMedical University of Vienna, Vienna, Austria.
Laura C CoatesUniversity of Oxford, Oxford, UK.ORCID 0000-0002-4756-663X
Laure GossecSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié Salpêtrière Hospital, AP-HP, Paris, France.ORCID 0000-0002-4528-310X
Remission/Flare in PsA Study Group
Amsterdam UMC Location Vrije Universiteit Amsterdam · NLCarol Davila University of Medicine and Pharmacy · ROCentre Hospitalier du Mans · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FRInserm · FRJohns Hopkins University · USMedical University of Vienna · ATNational University of Singapore · SGUniversity of Oxford · GBUniversity of Toronto · CA

Funding

Sample Processing and Immunoassay Research CoreP30AR070254 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI Antony Rosen · 2016 to 2026
$8.9M
NIAMS NIH HHS P30 AR070254
6 · The paper itself

Abstract

objectiveWe evaluated the psychometric properties of 3 patient-reported outcome measures to assess the physical function in psoriatic arthritis (PsA).

methodsData were available for the Health Assessment Questionnaire disability index (HAQ DI), the 12-item Short Form instrument physical component summary (SF-12 PCS), and the Psoriatic Arthritis Impact of Disease instrument functional capacity score (PsAID-FC). Data came from a longitudinal study in 14 countries of consecutive adults with definite PsA with ≥2 years of duration. The score distribution, construct validity, responsiveness, and thresholds of meaning of the patient-reported outcome measures were evaluated.

resultsAt baseline, 414 subjects (52% male) were analyzed. The mean ± SD age was 52.4 ± 12.5 years and duration of illness was 10.9 ± 8.1 years. Ceiling effects were noted in 31% and 21% of patients for HAQ DI and PsAID-FC, respectively; floor effects were minimal. All 3 patient-reported outcome measures met a priori hypotheses for construct validity. After a median follow-up of 4.1 (interquartile range 2.7) months in 350 patients, 27%, 54%, and 18% of patients reported themselves improved, not changed, and worsened, respectively. Change scores were statistically different for groups for worsening versus no-change for all patient-reported outcome measures. PsAID-FC was more sensitive to change than the other 2 patient-reported outcome measures. Comparing groups with worsening condition to no-change, the standardized response mean square ratios were HAQ DI 29.9, SF-12 PCS 16.7, and PsAID-FC 40.1.

conclusionHAQ DI, SF-12 PCS, and PsAID-FC are valid measures of physical function for PsA. PsAID-FC, a single question, performed similarly to the other patient-reported outcome measures and may be an additional option to measure PsA-specific physical function.

Indexed as

Health Status IndicatorsPatient Reported Outcome MeasuresAdultAgedArthritis, PsoriaticFemaleFunctional StatusHumansLongitudinal StudiesMaleMiddle AgedPredictive Value of TestsProspective StudiesPsychometricsReproducibility of ResultsTreatment Outcome

Identifiers

PMID31961492
PMCPMC7371516
OpenAlexW3001441289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.