Evidence map›Paper›PMID 31961429›Full record

ArticleFamily practice2020

Faecal immunochemical test-based colorectal cancer screening in Mexico: an initial experience.

José María Remes-Troche, Gabriela Hinojosa-Garza, Priscilla Espinosa-Tamez, Arturo Meixueiro-Daza, Peter Grube-Pagola, Katherine Van Loon, Michael B Potter, Martin Lajous

Abstract read
In one paragraph

Article in Family practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Colorectal Cancer Screening Program Results in Iran.Medical journal of the Islamic Republic of Iran · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

José María Remes-TrocheDepartamento de Gastroenterología, Instituto de Investigaciones Médico Biológicas, Universidad Veracruzana, Veracruz, México.
Gabriela Hinojosa-GarzaCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Mexico City, Mexico.
Priscilla Espinosa-TamezCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Mexico City, Mexico.
Arturo Meixueiro-DazaDepartamento de Gastroenterología, Instituto de Investigaciones Médico Biológicas, Universidad Veracruzana, Veracruz, México.
Peter Grube-PagolaDepartamento de Anatomía Patológica, Hospital de Alta Especialidad, Centro Médico Nacional «Adolfo Ruiz Cortines», Instituto Mexicano del Seguro Social, Veracruz, México.
Katherine Van LoonUCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, USA.
Michael B PotterSan Francisco Bay Area Collaborative Research Network, University of California San Francisco Clinical and Translational Science Institute, San Francisco, USA.
Martin LajousDepartamento de Gastroenterología, Instituto de Investigaciones Médico Biológicas, Universidad Veracruzana, Veracruz, México.

Funding

Mesoamerican Center for Population Health Research on Non-Communicable DiseaseP20CA210286 · NCI · MEXICO NATIONAL INSTITUTE OF PUBLIC HLTH · PI LAJOUS, MARTIN, LOPEZ-RIDAURA, RUY · 2016 to 2017
$490k
NCI NIH HHS P20 CA210286
6 · The paper itself

Abstract

backgroundIn middle-income countries, the burden of colorectal cancer (CRC) is increasing in parallel with resources for diagnosis and treatment. There is a potential benefit of CRC screening programs in Mexico.

objectiveSince there are no organized screening programs in the country, we explored the willingness of individuals to complete a faecal immunochemical testing (FIT) based CRC screening program and its potential benefit in Mexico.

methodsWe conducted a CRC screening program pilot in Veracruz, Mexico, during 2015-16 using FIT. Individuals with FIT results >100 ng of haemoglobin/ml buffer were referred for diagnostic colonoscopy.

resultsOf 473 FIT kits distributed to adults aged 50-75, 85.8% (406) were completed by participants and analysed in the laboratory. Of these, 5.9% (24/406) of test results showed >100 ng haemoglobin/ml. Twenty-one participants completed colonoscopy. The positive predictive value of FIT >100 ng haemoglobin/ml for premalignant lesions was 33%.

conclusionThese results provide preliminary evidence of the willingness of individuals to complete FIT-based CRC screening program in Mexico. However, further evaluation of health systems resources will be needed prior to large-scale implementation of CRC screening programs.

Indexed as

Occult BloodAgedColonoscopyColorectal NeoplasmsEarly Detection of CancerFemaleHemoglobinsHumansImmunochemistryMaleMexicoMiddle AgedHemoglobinsBiopsycolonoscopycolorectal neoplasmsearly detection of cancerMexicooccult blood

Identifiers

PMID31961429
PMCPMC7377340

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.