ArticleEmerging infectious diseases2020
Characteristics of Patients with Acute Flaccid Myelitis, United States, 2015-2018.
Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 43 citations in OpenAlex.
- mRNA vaccine expressing enterovirus D68 virus-like particles induces potent neutralizing antibodies and protects against infection.Molecular therapy. Nucleic acids · 2025Article
- Multimodal Surveillance Model for Enterovirus D68 Respiratory Disease and Acute Flaccid Myelitis among Children in Colorado, USA, 2022.Emerging infectious diseases · 2024Review
- Surveillance for Acute Flaccid Myelitis - United States, 2018-2022.MMWR. Morbidity and mortality weekly report · 2024Article
- Serum 25-Hydroxy Vitamin D Levels in Children with Acute Respiratory Infections Caused by Respiratory Virus or Atypical Pathogen Infection.Nutrients · 2023Article
- Acute flaccid myelitis: not uncommon in rural Uganda?Brain communications · 2023Article
- National Surveillance for Acute Flaccid Myelitis - United States, 2018-2020.MMWR. Morbidity and mortality weekly report · 2021Article
- Lower Extremity Nerve Transfers in Acute Flaccid Myelitis Patients: A Case Series.Plastic and reconstructive surgery. Global open · 2021Article
- Epidemiological dynamics of enterovirus D68 in the US: implications for acute flaccid myelitis.medRxiv : the preprint server for health sciences · 2021Article
- Acute flaccid myelitis: cause, diagnosis, and management.Lancet (London, England) · 2021Review
- Central nervous system as a target of novel coronavirus infections: Potential routes of entry and pathogenic mechanisms.Journal of biosciences · 2021Review
- Acute flaccid myelitis in Canada, 2018 to 2019.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2020Article
- Enterovirus D68-Associated Acute Flaccid Myelitis, United States, 2020.Emerging infectious diseases · 2020Article
- Vital Signs: Clinical Characteristics of Patients with Confirmed Acute Flaccid Myelitis, United States, 2018.MMWR. Morbidity and mortality weekly report · 2020Article
- Enterovirus D68 molecular and cellular biology and pathogenesis.The Journal of biological chemistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Observed peaks of acute flaccid myelitis (AFM) cases have occurred biennially since 2014 in the United States. We aimed to determine if AFM etiology differed between peak and nonpeak years, considering that clinical features of AFM differ by virus etiology. We compared clinical and laboratory characteristics of AFM cases that occurred during peak (2016 and 2018, n = 366) and nonpeak (2015 and 2017, n = 50) years. AFM patients in peak years were younger (5.2 years) than those in nonpeak years (8.3 years). A higher percentage of patients in peak years than nonpeak years had pleocytosis (86% vs. 60%), upper extremity involvement (33% vs. 16%), and an illness preceding limb weakness (90% vs. 62%) and were positive for enterovirus or rhinovirus RNA (38% vs. 16%). Enterovirus D68 infection was associated with AFM only in peak years. Our findings suggest AFM etiology differs between peak and nonpeak years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.