Evidence map›Paper›PMID 31961029›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020

Pd-Catalyzed Asymmetric N-Allylation of Amino Acid Esters with Exceptional Levels of Catalyst Control: Stereo-Divergent Synthesis of ProM-15 and Related Bicyclic Dipeptide Mimetics.

Stephan Dohmen, Martin Reiher, Dominik Albat, Sema Akyol, Matthias Barone, Jörg-Martin Neudörfl, Ronald Kühne, Hans-Günther Schmalz

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Ena/VASP-EVH1 inhibition prevents chemotaxis and metastasis by blocking the EVH1-WAVE2 interaction.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephan DohmenDepartment of Chemistry, University of Cologne, Greinstrasse 4, 50939, Köln, Germany.
Martin ReiherDepartment of Chemistry, University of Cologne, Greinstrasse 4, 50939, Köln, Germany.
Dominik AlbatDepartment of Chemistry, University of Cologne, Greinstrasse 4, 50939, Köln, Germany.
Sema AkyolDepartment of Chemistry, University of Cologne, Greinstrasse 4, 50939, Köln, Germany.
Matthias BaroneLeibniz-Institut für Molekulare Pharmakologie (FMP), 13125, Berlin, Germany.
Jörg-Martin NeudörflDepartment of Chemistry, University of Cologne, Greinstrasse 4, 50939, Köln, Germany.
Ronald KühneLeibniz-Institut für Molekulare Pharmakologie (FMP), 13125, Berlin, Germany.
Hans-Günther SchmalzDepartment of Chemistry, University of Cologne, Greinstrasse 4, 50939, Köln, Germany.ORCID http://orcid.org/0000-0003-0489-1827

Funding

Bundesministerium für Forschung und Technologie 16GW0187 "EnVision"
6 · The paper itself

Abstract

A general and powerful method for the stereo-controlled Pd-catalyzed N-allylation of amino acid esters is reported, as a previously largely unsolved synthetic challenge. Employing a new class of tartaric acid-derived C

Indexed as

AlanineAmino AcidsCatalysisCrystallography, X-RayCycloaddition ReactionDipeptidesEstersLigandsModels, MolecularMolecular StructureOxidation-ReductionPalladiumProlineStereoisomerismAlanineAmino AcidsDipeptidesEstersLigandsPalladiumProlineasymmetric catalysischiral diphosphine ligandspeptide mimeticsprotein interactionstransition-metal catalysis

Identifiers

PMID31961029
PMCPMC7078984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.