Evidence map›Paper›PMID 31960953›Full record

Trial reportThe British journal of surgery2020

Carcinoembryonic antigen-specific, fluorescent image-guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer.

D P Schaap, K S de Valk, M M Deken, R P J Meijer, J Burggraaf, A L Vahrmeijer, M Kusters, SGM-101 study group

Open access · hybridAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in The British journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Intraoperative molecular imaging of colorectal lung metastases with SGM-101: a feasibility study.European journal of nuclear medicine and molecular imaging · 2024
    Trial
  5. Review
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  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
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  15. Precision Surgery Guided by Intraoperative Molecular Imaging.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

D P SchaapDepartment of Surgery, Catharina Hospital, Eindhoven, Netherlands.ORCID 0000-0001-5113-6424
K S de ValkCentre for Human Drug Research, Leiden, Netherlands.
M M DekenCentre for Human Drug Research, Leiden, Netherlands.
R P J MeijerCentre for Human Drug Research, Leiden, Netherlands.
J BurggraafCentre for Human Drug Research, Leiden, Netherlands.
A L VahrmeijerDepartment of Surgery, Leiden University Medical Centre, Leiden, Netherlands.ORCID 0000-0001-9370-0011
M KustersDepartment of Surgery, Amsterdam University Medical Centres, location VUmc, Amsterdam, Netherlands.
SGM-101 study group
Leiden University Medical Center · NLRadboud University Nijmegen · NLErasmus MC · NLAmsterdam University Medical Centers · NLSurgimab (France) · FRCentre for Human Drug Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This multicentre pilot study investigated the role of peroperative carcinoembryonic antigen (CEA)-specific fluorescence imaging during cytoreductive surgery-hyperthermic intraperitoneal chemotherapy surgery in peritoneal metastasized colorectal cancer. A correct change in peritoneal carcinomatosis index (PCI) owing to fluorescence imaging was seen in four of the 14 included patients. The use of SGM-101 in patients with peritoneally metastasized colorectal carcinoma is feasible, and allows intraoperative detection of tumour deposits and alteration of the PCI. Augmented reality guidance.

Indexed as

AdultAgedCarcinoembryonic AntigenColorectal NeoplasmsCombined Modality TherapyCytoreduction Surgical ProceduresFemaleFluorescent Antibody TechniqueFluorescent DyesHumansHyperthermia, InducedMaleMiddle AgedOptical ImagingPilot ProjectsCarcinoembryonic AntigenFluorescent Dyes

Identifiers

PMID31960953
PMCPMC7079046
OpenAlexW3000827302

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.