Evidence map›Paper›PMID 31960794›Full record

ArticleeLife2020

Development of a confinable gene drive system in the human disease vector

Ming Li, Ting Yang, Nikolay P Kandul, Michelle Bui, Stephanie Gamez, Robyn Raban, Jared Bennett, Héctor M Sánchez C, Gregory C Lanzaro, Hanno Schmidt and 3 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed
33.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 248 citations in OpenAlex.

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  14. A single-nucleus transcriptomic atlas of the adultbioRxiv : the preprint server for biology · 2025
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  19. Differential elimination of marked sex chromosomes enables production of nontransgenic male mosquitoes in a single strain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ming LiSection of Cell and Developmental Biology, University of California, San Diego, San Diego, United States.ORCID 0000-0002-7578-4968
Ting YangSection of Cell and Developmental Biology, University of California, San Diego, San Diego, United States.ORCID 0000-0001-7201-4231
Nikolay P KandulSection of Cell and Developmental Biology, University of California, San Diego, San Diego, United States.
Michelle BuiSection of Cell and Developmental Biology, University of California, San Diego, San Diego, United States.
Stephanie GamezSection of Cell and Developmental Biology, University of California, San Diego, San Diego, United States.
Robyn RabanSection of Cell and Developmental Biology, University of California, San Diego, San Diego, United States.ORCID 0000-0002-5648-6770
Jared BennettDepartment of Biophysics, University of California, Berkeley, Berkeley, United States.
Héctor M Sánchez CDivision of Epidemiology and Biostatistics, School of Public Health, University of California, Berkeley, Berkeley, United States.
Gregory C LanzaroVector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, United States.
Hanno SchmidtVector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, United States.ORCID 0000-0001-8915-891X
Yoosook LeeVector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, United States.
John M MarshallDivision of Epidemiology and Biostatistics, School of Public Health, University of California, Berkeley, Berkeley, United States.ORCID 0000-0003-0603-7341
Omar S AkbariSection of Cell and Developmental Biology, University of California, San Diego, San Diego, United States.ORCID 0000-0002-6853-9884
University of California San Diego · USVector (United States) · USUniversity of California, Berkeley · USInnovative Genomics Institute · US

Funding

CDC HHS 1U01CK000516NCEZID CDC HHS U01 CK000516
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Drive TechnologyAedesAnimalsAnimals, Genetically ModifiedCRISPR-Cas SystemsFemaleMaleMosquito VectorsRNA, Guide, CRISPR-Cas SystemsRNA, Guide, CRISPR-Cas SystemsAedes aegyptiCas9CRISPRdengueepidemiologyglobal healthsplit gene drives

Identifiers

PMID31960794
PMCPMC6974361
OpenAlexW3000702515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.