Evidence map›Paper›PMID 31960619›Full record

ArticlePhysiological reports2020

Impact of different fixed flow sampling protocols on flow-independent exhaled nitric oxide parameter estimates using the Bayesian dynamic two-compartment model.

Patrick Muchmore, Shujing Xu, Paul Marjoram, Edward B Rappaport, Jingying Weng, Noa Molshatzki, Sandrah P Eckel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patrick MuchmoreDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Shujing XuDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Paul MarjoramDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Edward B RappaportDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Jingying WengDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Noa MolshatzkiDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Sandrah P EckelDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0001-6050-7880

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Training Grant in Genomic Analysis and InterpretationT32ES013678 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GAUDERMAN, WILLIAM JAMES, MCCONNELL, ROB S · 2006 to 2023
$5.6M
Early detection of adverse respiratory effects from air pollutionR01ES023262 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BERHANE, KIROS T, GILLILAND, FRANK D. · 2013 to 2016
$2.0M
Statistical methods for exhaled breath biomarkers in environmental epidemiologyR01ES027860 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ECKEL, SANDRAH PROCTOR · 2017 to 2019
$1.1M
NIEHS NIH HHS P30 ES007048NIEHS NIH HHS R01 ES023262NIEHS NIH HHS R01ES023262NIEHS NIH HHS R01 ES027860NIEHS NIH HHS R01ES027860NIEHS NIH HHS T32 ES013678NIEHS NIH HHS T32ES013678
6 · The paper itself

Abstract

Exhaled nitric oxide (FeNO) is an established respiratory biomarker with clinical applications in the diagnosis and management of asthma. Because FeNO depends strongly on the flow (exhalation) rate, early protocols specified that measurements should be taken when subjects exhaled at a fixed rate of 50 ml/s. Subsequently, multiple flow (or "extended") protocols were introduced which measure FeNO across a range of fixed flow rates, allowing estimation of parameters including C

Indexed as

AdolescentAsthmaBayes TheoremBreath TestsBronchiExhalationFemaleHumansMaleMarkov ChainsMonte Carlo MethodNitric OxidePulmonary AlveoliNitric OxideBayesian inferenceexhaled breathFeNOsampling protocol

Identifiers

PMID31960619
PMCPMC6971414

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.