Evidence map›Paper›PMID 31960592›Full record

ArticlePhysiological reports2020

Calcium-sensing receptor regulates intestinal dipeptide absorption via Ca

Jingyu Xu, Andre Zeug, Brigitte Riederer, Sunil Yeruva, Oliver Griesbeck, Hannelore Daniel, Biguang Tuo, Evgeni Ponimaskin, Hui Dong, Ursula Seidler

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Monosodium glutamate-mediated CaPhysiological reports · 2026
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  10. CaFrontiers in pharmacology · 2022
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Jingyu XuDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Andre ZeugCellular Neurophysiology, Hannover Medical School, Hannover, Germany.
Brigitte RiedererDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Sunil YeruvaDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Oliver GriesbeckMax-Planck-Institut für Neurobiologie, Martinsried, Germany.
Hannelore DanielNutritional Physiology, Technical University of Munich, Freising, Germany.
Biguang TuoResearch Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Evgeni PonimaskinCellular Neurophysiology, Hannover Medical School, Hannover, Germany.
Hui DongDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-2244-2040
Ursula SeidlerDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Medizinische Hochschule Hannover · DEZunyi Medical University · CNLeibniz-Institute for Food Systems Biology at the Technical University of Munich · DEMax Planck Institute of Neurobiology · DEUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although absorption of di- and tripeptides into intestinal epithelial cells occurs via the peptide transporter 1 (PEPT1, also called solute carrier family 15 member 1 (SLC15A1)), the detailed regulatory mechanisms are not fully understood. We examined: (a) whether dipeptide absorption in villous enterocytes is associated with a rise in cytosolic Ca

Indexed as

AnimalsCalcium SignalingClotrimazoleDipeptidesEnterocytesEstrenesIntestinal AbsorptionIntestinal MucosaJejunumMiceMice, KnockoutMucous MembraneNaphthalenesPeptide Transporter 1Phosphodiesterase InhibitorsPotassium Channels, Calcium-Activated1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dioneClotrimazoleDipeptidesEstrenesglycylsarcosineN-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamineNaphthalenesPeptide Transporter 1Phosphodiesterase InhibitorsPotassium Channels, Calcium-ActivatedPyrrolidinonesReceptors, Calcium-SensingSlc15a1 protein, mouseSpermineType C Phospholipasescalcium sensing receptordipeptide absorptionintestineintracellular calcium signalingpeptide transporter 1

Identifiers

PMID31960592
PMCPMC6971415
OpenAlexW3002692650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.