Evidence map›Paper›PMID 31960589›Full record

ArticleJournal of the International AIDS Society2020

Linkages to HIV confirmatory testing and antiretroviral therapy after online, supervised, HIV self-testing among Thai men who have sex with men and transgender women.

Nittaya Phanuphak, Jureeporn Jantarapakde, Linrada Himmad, Thanthip Sungsing, Ratchadaporn Meksena, Sangusa Phomthong, Petchfa Phoseeta, Sumitr Tongmuang, Pravit Mingkwanrungruang, Dusita Meekrua and 8 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Nittaya PhanuphakPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.ORCID 0000-0002-0036-3165
Jureeporn JantarapakdePREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.ORCID 0000-0001-5074-7450
Linrada HimmadPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Thanthip SungsingPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Ratchadaporn MeksenaPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Sangusa PhomthongPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Petchfa PhoseetaPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Sumitr TongmuangPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Pravit MingkwanrungruangPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Dusita MeekruaService Workers IN Group (SWING) Foundation, Bangkok, Thailand.
Supachai SukthongsaSWING Foundation, Pattaya, Thailand.
Somporn HongwiangchanRainbow Sky Association of Thailand, Bangkok, Thailand.
Nutchanin UpanunSisters Foundation, Pattaya, Thailand.
Supunnee JirajariyavejTaksin Hospital, Bangkok, Thailand.
Tanate JadwattanakulQueen Savang Vadhana Memorial Hospital, Pattaya, Thailand.
Supphadith BarisriAnonymous Clinic Laboratory, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Tippawan PankamAnonymous Clinic Laboratory, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Praphan PhanuphakPREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Thai Red Cross Society · THBangkok Hospital · THPayap University · THQueen Saovabha Memorial Institute · THSiam University · THThai Health Promotion Foundation · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOnline, supervised, HIV self-testing has potential to reach men who have sex with men (MSM) and transgender women (TGW) who never tested before and who had high HIV-positive yield. We studied linkages to HIV confirmatory test and antiretroviral therapy (ART) initiation among Thai MSM and TGW who chose online and/or offline platforms for HIV testing and factors associated with unsuccessful linkages.

methodsMSM and TGW were enrolled from Bangkok Metropolitan Region and Pattaya during December 2015 to June 2017 and followed for 12 months. Participants could choose between: 1) offline HIV counselling and testing (Offline group), 2) online pre-test counselling and offline HIV testing (Mixed group) and 3) online counselling and online, supervised, HIV self-testing (Online group). Sociodemographic data, risk behaviour and social network use characteristics were collected by self-administered questionnaires. Linkages to HIV confirmatory testing and/or ART initiation were collected from participants who tested reactive/positive at baseline and during study follow-up. Modified Poisson regression models identified covariates for poor retention and unsuccessful ART initiation.

resultsOf 465 MSM and 99 TGW, 200 self-selected the Offline group, 156 the Mixed group and 208 the Online group. The Online group demonstrated highest HIV prevalence (15.0% vs. 13.0% vs. 3.4%) and high HIV incidence (5.1 vs. 8.3 vs. 3.2 per 100 person-years), compared to the Offline and Mixed groups. Among 60 baseline HIV positive and 18 seroconversion participants, successful ART initiation in the Online group (52.8%) was lower than the Offline (84.8%) and Mixed groups (77.8%). Factors associated with unsuccessful ART initiation included choosing to be in the Online group (aRR 3.94, 95% CI 1.07 to 14.52), <17 years old at first sex (aRR 3.02, 95% CI 1.15 to 7.92), amphetamine-type stimulants use in the past six months (aRR 3.6, 95% CI 1.22 to 10.64) and no/single sex partner (aRR 3.84, 95%CI 1.36 to 10.83) in the past six months.

conclusionsOnline, supervised, HIV self-testing allowed more MSM and TGW to know their HIV status. However, linkages to confirmatory test and ART initiation once tested HIV-reactive are key challenges. Alternative options to bring HIV test confirmation, prevention and ART services to these individuals after HIV self-testing are needed.

Indexed as

AdultAnti-HIV AgentsFemaleHIV InfectionsHomosexuality, MaleHumansMaleMass ScreeningPrevalenceRisk-TakingSerologic TestsSexual BehaviorSexual PartnersThailandTransgender PersonsYoung AdultAnti-HIV AgentsHIV self-testinglink to caremen who have sex with menonlinetransgender women

Identifiers

PMID31960589
PMCPMC6970936
OpenAlexW3001515194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.