ArticleNature microbiology2020
Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 51 citations in OpenAlex.
- Canonical and noncanonical autophagy in immunity.Immunity · 2026Review
- Membrane atg8ylation and autophagy in protection against Mycobacterium tuberculosis.Journal of immunology (Baltimore, Md. : 1950) · 2026Review
- ATG7 in innate immune cells is required for host defense against nontuberculous mycobacterial pulmonary infections.Nature communications · 2025Article
- Article
- Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival.The Journal of clinical investigation · 2025Article
- Article
- Autophagy and Bacterial infections.Autophagy reports · 2025Review
- Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function.bioRxiv : the preprint server for biology · 2024Article
- ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease.Autophagy · 2024Article
- The nonautophagic functions of autophagy-related proteins.Autophagy · 2024Review
- PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages.Cell reports · 2024Article
- Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis infection in mice.Nature microbiology · 2024Article
- Bacteria-instructed B cells cross-prime naïve CD8EMBO reports · 2023Article
- Inside-out assembly of viral antigens for the enhanced vaccination.Signal transduction and targeted therapy · 2023Article
- T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity.Immunity · 2023Article
- Myeloid autophagy genes protect mice against fatal TNF- and LPS-induced cytokine storm syndromes.Autophagy · 2023Article
- Autophagy and Its Lineage-Specific Roles in the Hematopoietic System.Oxidative medicine and cellular longevity · 2023Review
- Atg8ylation as a host-protective mechanism againstFrontiers in tuberculosis · 2023Article
- A guide to membrane atg8ylation and autophagy with reflections on immunity.The Journal of cell biology · 2022Article
- Intestinal antiviral signaling is controlled by autophagy geneAutophagy · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
20 authors at 5 institutions in 3 countries.
Ya-Ting WangDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. wang.yating@wustl.edu.ORCID http://orcid.org/0000-0002-5057-4083
Konstantin ZaitsevDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0003-3749-0886
Qun LuDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Shan LiDepartment of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO, USA.
W Timothy SchaiffDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Ki-Wook KimDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Lindsay DroitDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Craig B WilenDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0003-2495-9403
Chandni DesaiDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Dale R BalceDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Robert C OrchardDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0001-8216-4946
Anthony OrvedahlDepartment of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA.
Sunmin ParkDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Darren KreamalmeyerDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Scott A HandleyDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
John D PfeiferLauren V. Ackerman Laboratory of Surgical Pathology, Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University Medical Center, St Louis, MO, USA.
Megan T BaldridgeDepartment of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-7030-6131
Maxim N ArtyomovDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Christina L StallingsDepartment of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA. stallings@wustl.edu.ORCID http://orcid.org/0000-0002-2747-5618
Herbert W VirginDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. svirgin@vir.bio.ORCID http://orcid.org/0000-0001-8580-7628
Washington University in St. Louis · USITMO University · RUUniversity of Illinois Urbana-Champaign · USWashington University Medical Center · USYunnan University · CN
Funding
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0MRP5: Chemical proteomic discovery of small-molecule probes for autophagy proteinsU19AI142784 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VIRGIN, HERBERT W · 2019 to 2023
$36.9MGenetic and Pathway Analysis CoreU19AI109725 · NIAID · WASHINGTON UNIVERSITY · PI VIRGIN, HERBERT W · 2014 to 2018
$32.7MAutophagy proteins in the immune response to Mycobacterium tuberculosis infectionR01AI132697 · NIAID · WASHINGTON UNIVERSITY · PI STALLINGS, CHRISTINA LEIGH · 2019 to 2023
$2.4MIdentification and Characterization of Norovirus Cofactors for EntryR00DK116666 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI ORCHARD, ROBERT C. · 2018 to 2020
$747kFoundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) K08 A128043Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) U19 AI42784NCI NIH HHS P30 CA091842NIAID NIH HHS R01 AI132697NIAID NIH HHS U19 AI109725NIAID NIH HHS U19 AI142784NIDDK NIH HHS R00 DK116666
Abstract
Innate and adaptive immune responses that prime myeloid cells, such as macrophages, protect against pathogens
Indexed as
AnimalsAutophagyAutophagy-Related ProteinsBeclin-1Cell ProliferationDisease SusceptibilityFemaleGenetic Predisposition to DiseaseInterferon-gammaListeria monocytogenesListeriosisMacrophage ActivationMacrophages, PeritonealMaleMiceMice, Inbred C57BLAutophagy-Related ProteinsBeclin-1Becn1 protein, mouseInterferon-gammaRb1cc1 protein, mouse
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.