Evidence map›Paper›PMID 31959970›Full record

Observational studyNature microbiology2020

Commensal Escherichia coli are a reservoir for the transfer of XDR plasmids into epidemic fluoroquinolone-resistant Shigella sonnei.

Pham Thanh Duy, To Nguyen Thi Nguyen, Duong Vu Thuy, Hao Chung The, Felicity Alcock, Christine Boinett, Ho Ngoc Dan Thanh, Ha Thanh Tuyen, Guy E Thwaites, Maia A Rabaa and 1 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 68 citations in OpenAlex.

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  13. Antioxidants (Basel, Switzerland) · 2025
    Article
  14. Community gut colonization byFrontiers in cellular and infection microbiology · 2025
    Article
  15. Genomic characterization of a clonal emergentApplied and environmental microbiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Pham Thanh DuyThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
To Nguyen Thi NguyenThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Duong Vu ThuyThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Hao Chung TheThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0002-4028-4074
Felicity AlcockThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0002-3983-6097
Christine BoinettThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Ho Ngoc Dan ThanhThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Ha Thanh TuyenThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Guy E ThwaitesThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Maia A Rabaa *The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0003-0529-2228
Stephen Baker *The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam. sgb47@medschl.cam.ac.uk.ORCID http://orcid.org/0000-0003-1308-5755
Oxford University Clinical Research Unit · VNUniversity of Oxford · GBUniversity of Cambridge · GB

Funding

Wellcome Trust 100087Wellcome Trust 100087/Z/12/Z
6 · The paper itself

Abstract

Despite the sporadic detection of fluoroquinolone-resistant Shigella in Asia in the early 2000s and the subsequent global spread of ciprofloxacin-resistant (cipR) Shigella sonnei from 2010, fluoroquinolones remain the recommended therapy for shigellosis

Indexed as

ChildCiprofloxacinDigestive SystemDisease ReservoirsDrug Resistance, Multiple, BacterialDysentery, BacillaryEpidemicsEscherichia coliFluoroquinolonesGenes, BacterialHumansPhylogenyR FactorsShigella sonneiSymbiosisVietnamCiprofloxacinFluoroquinolones

Identifiers

PMID31959970
PMCPMC6992430
OpenAlexW3000372921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.