Evidence map›Paper›PMID 31959967›Full record

ArticleNature microbiology2020

Selective sequestration of signalling proteins in a membraneless organelle reinforces the spatial regulation of asymmetry in Caulobacter crescentus.

Keren Lasker, Lexy von Diezmann, Xiaofeng Zhou, Daniel G Ahrens, Thomas H Mann, W E Moerner, Lucy Shapiro

Open access · greenAbstract read
In one paragraph

Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 118 citations in OpenAlex.

  1. The polar landscape of bacterial pathogens and predators.Current opinion in microbiology · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Mechanisms and Pathological Significance of Liquid-Liquid Phase Separation in Bacteria.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Molecular biology of the cell · 2024
    Article
  19. Review
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Keren Lasker *Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA.
Lexy von Diezmann *Department of Chemistry, Stanford University, Stanford, CA, USA.
Xiaofeng ZhouDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA.
Daniel G AhrensDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA.
Thomas H MannDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA.
W E MoernerDepartment of Chemistry, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-2830-209X
Lucy ShapiroDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA. shapiro@stanford.edu.ORCID http://orcid.org/0000-0002-0445-067X
Stanford University · USChan Zuckerberg Initiative (United States) · USSalk Institute for Biological Studies · USUniversity of Utah · US

Funding

Supplement to Enhance Wellness and Resiliency in the Graduate EnvironmentT32GM007276 · NIGMS · STANFORD UNIVERSITY · PI MORRISON, ASHBY J. · 1985 to 2023
$32.9M
VECTOR COREP30NS069375 · NINDS · STANFORD UNIVERSITY · PI STEINBERG, GARY K · 2011 to 2019
$6.3M
Single-Molecule Imaging for Cell Biology and Super-Resolution MicroscopyR35GM118067 · NIGMS · STANFORD UNIVERSITY · PI MOERNER, WILLIAM E · 2016 to 2025
$6.2M
Subcellular architecture of regulatory protein complexes at the bacterial poleR01GM086196 · NIGMS · STANFORD UNIVERSITY · PI MOERNER, WILLIAM E, SHAPIRO, LUCILLE · 2008 to 2015
$4.7M
Integration of regulatory networks and subcellular architecture to control the Caulobacter cell cycleR35GM118071 · NIGMS · STANFORD UNIVERSITY · PI SHAPIRO, LUCILLE · 2016 to 2020
$3.2M
NIGMS NIH HHS R01 GM086196NIGMS NIH HHS R35 GM118067NIGMS NIH HHS R35 GM118071NIGMS NIH HHS T32 GM007276NINDS NIH HHS P30 NS069375U.S. Department of Health & Human Services | National Institutes of Health (NIH) T32GM007276
6 · The paper itself

Abstract

Selective recruitment and concentration of signalling proteins within membraneless compartments is a ubiquitous mechanism for subcellular organization

Indexed as

Bacterial ProteinsCaulobacter crescentusCell CycleCell DivisionCell PolarityGene Expression Regulation, BacterialHistidine KinaseOrganellesPhosphotransferasesSignal TransductionTranscription FactorsBacterial ProteinsHistidine KinasePhosphotransferasesTranscription Factors

Identifiers

PMID31959967
PMCPMC7549192
OpenAlexW2999515100

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.