SynthesisScientific reports2020
Adverse events associated with peanut oral immunotherapy in children - a systematic review and meta-analysis.
Synthesis in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Safety and efficiency of peanut oral immunotherapy in preschool children with slow up-dosing and low maintenance dosing: a randomised controlled trial.The Lancet regional health. Europe · 2026Article
- Oral immunotherapy for peanut allergy: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Peanut oral immunotherapy at a single academic medical center using a volume-based approach with store-purchased peanut products.The journal of allergy and clinical immunology. Global · 2026Article
- Predictors of Long-Term Desensitization in Children Treated with Oral Immunotherapy for Food Allergy: A Real-World Cohort Study.Journal of clinical medicine · 2025Article
- Food oral immunotherapy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025Review
- Peanut Allergy in Children-Is Prevention Better than Cure?Nutrients · 2024Review
- Recent advances in food allergen immunotherapy.Clinical and experimental pediatrics · 2024Article
- The Future of Food Allergy Management: Advancements in Therapies.Current allergy and asthma reports · 2024Review
- Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy.Cell reports. Medicine · 2024Article
- IL-4 receptor alpha signaling alters oral food challenge and immunotherapy outcomes in mice.The Journal of allergy and clinical immunology · 2023Article
- Anaphylaxis knowledge gaps and future research priorities: A consensus report.The Journal of allergy and clinical immunology · 2022Article
- Review
- Treatment Approaches to Food Allergy.Handbook of experimental pharmacology · 2022Review
- Oral Immunotherapy in Children: Clinical Considerations and Practical Management.Journal of asthma and allergy · 2021Review
- Oral immunotherapy for peanut allergy: The con argument.The World Allergy Organization journal · 2020Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While peanut oral immunotherapy (POIT) represents a promising treatment for peanut allergies in children, safety concerns remain a common barrier to widespread adoption. We aimed to systematically assess available evidence to determine the risk and frequency of adverse events occurring during POIT, and examine study-level characteristics associated with their occurrence and severity. A systematic search of MEDLINE, EMBASE, and Web of Science was conducted through April 2019. Controlled and non-controlled studies evaluating POIT were eligible. Twenty-seven studies, involving 1488 subjects, were included. Adverse events to POIT were common and led to treatment discontinuation in 6.6% of children (95% CI 4.4-9.0; 27 studies, I
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.