Evidence map›Paper›PMID 31959322›Full record

ArticleAmerican journal of preventive medicine2020

Opioid Prescribing Patterns Before Fatal Opioid Overdose.

Ali B Abbasi, Elizabeth Salisbury-Afshar, Craig E Berberet, Jennifer E Layden, Mai T Pho

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Hospital Care for Opioid use in Illinois, 2016-2019.The journal of behavioral health services & research · 2021
    Article
  7. Article
  8. Article
  9. Incidence of opioid use disorder in the year after discharge from an emergency department encounter.Journal of the American College of Emergency Physicians open · 2021
    Article
  10. Application of Distributed Agent-based Modeling to Investigate Opioid Use Outcomes in Justice Involved Populations.IEEE International Symposium on Parallel & Distributed Processing, Workshops and Phd Forum : [proceedings]. IEEE International Symposium on Parallel & Distributed Processing, Workshops and Phd Forum · 2021
    Article
  11. Opioids and Chronic Pain: An Analytic Review of the Clinical Evidence.Frontiers in pain research (Lausanne, Switzerland) · 2021
    Review
  12. Article
  13. Community Versus Hospital Opioid-Related Overdose Deaths in Illinois.Public health reports (Washington, D.C. : 1974)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali B AbbasiPritzker School of Medicine, University of Chicago, Chicago, Illinois. Electronic address: aba28@uchicago.edu.
Elizabeth Salisbury-AfsharCenter for Addiction Research and Effective Solutions, American Institutes for Research, Washington, D.C.
Craig E BerberetPrescription Monitoring Program, Illinois Department of Human Services, Springfield, Illinois.
Jennifer E LaydenOffice of the Director, Illinois Department of Public Health, Chicago, Illinois.
Mai T PhoDepartment of Medicine, University of Chicago Medical Center, Chicago, Illinois.

Funding

Reducing Opioid Mortality in Illinois (ROMI)UG1DA050066 · NIDA · UNIVERSITY OF CHICAGO · PI PHO, MAI TUYET, POLLACK, HAROLD ALEXANDER · 2019 to 2023
$15.5M
Ending transmission of HIV, HCV, and STDs and overdose in rural communities of people who inject drugs (ETHIC)UG3DA044829 · NIDA · UNIVERSITY OF CHICAGO · PI JENKINS, WILEY, PHO, MAI TUYET · 2017 to 2018
$1.1M
Optimizing Patient-Oriented Outcomes for Chronic Hepatitis CR00HS022433 · AHRQ · UNIVERSITY OF CHICAGO · PI PHO, MAI TUYET · 2015 to 2017
$739k
AHRQ HHS R00 HS022433NIDA NIH HHS UG1 DA050066NIDA NIH HHS UG3 DA044829
6 · The paper itself

Abstract

introductionAlthough opioid prescribing has decreased since 2010, overdose deaths involving illicit opioids have continued to rise. This study explores prescribing patterns before fatal overdose of decedents who died of prescription and illicit opioid overdoses.

methodsThis retrospective cohort study was conducted in 2019 and included all 1,893 Illinois residents who died of an opioid-related overdose in 2016. Each decedent was linked to any existing Prescription Monitoring Program records, calculating weekly morphine milligram equivalents for 52 weeks before overdose.

resultsAmong the 1,893 fatal opioid overdoses, 309 involved any prescription opioid and 1,461 involved illicit opioids without the involvement of prescription opioids. The death rate because of illicit opioids was 23/100,000 among black residents versus 10.5/100,000 among whites. During the last year of life, 76% of prescription opioid decedents filled any opioid prescription totaling 10.7 prescriptions per decedent, compared with 36% of illicit opioid decedents totaling 2.6 prescriptions per decedent. During the last week of life, 33% of prescription opioid decedents filled an opioid prescription totaling 0.42 prescriptions per decedent, compared with 4% of illicit opioid decedents totaling 0.05 prescriptions per decedent.

conclusionsPrescribing patterns alone may not be sufficient to identify patients who are at high risk for opioid overdose, especially for those using illicit opioids. Interventions aimed at reducing opioid overdoses should take into account different patterns of opioid prescribing associated with illicit and prescription opioid overdose deaths and be designed around the local characteristics of the opioid overdose epidemic.

Indexed as

AdultAnalgesics, OpioidDrug OverdoseFemaleHumansIllicit DrugsIllinoisMaleMiddle AgedPractice Patterns, Physicians'Prescription Drug MisuseRetrospective StudiesAnalgesics, OpioidIllicit Drugs

Identifiers

PMID31959322
PMCPMC6986381

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.