ArticleBMC research notes2020
Renal detection of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in malaria associated acute kidney injury: a retrospective case-control study.
Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Clinical characteristics and outcome of malaria-associated acute kidney injury in adult patients: a systematic review and meta analysis.Malaria journal · 2026Pooled it
- Is there evidence of sustained human-mosquito-human transmission of the zoonotic malaria Plasmodium knowlesi? A systematic literature review.Malaria journal · 2022Pooled it
- Trial
- Animal Models of Malaria-Associated Acute Kidney Injury.Seminars in nephrology · 2025Review
- Cerebral manifestations of falciparum malaria in adults: more than meets the eye.Trends in parasitology · 2025Review
- Article
- Review
- Review
- Inter-Population Genetic Diversity and Clustering ofTropical medicine and infectious disease · 2023Article
- The kidney-brain pathogenic axis in severe falciparum malaria.Trends in parasitology · 2023Review
- Article
- The Impact of Geographical Variation inTropical medicine and infectious disease · 2023Article
- A novel multiplex qPCR assay for clinical diagnosis of non-human malaria parasites-Frontiers in veterinary science · 2023Article
- Challenges in Understanding the Bionomics of Indian Malaria Vectors.The American journal of tropical medicine and hygiene · 2022Article
- Narrative Review of the Control and Prevention of Knowlesi Malaria.Tropical medicine and infectious disease · 2022Review
- Kidney complications of parasitic diseases.Nature reviews. Nephrology · 2022Review
- Biochemical characteristics of patients with imported malaria.Frontiers in cellular and infection microbiology · 2022Article
- Heme Burden and Ensuing Mechanisms That Protect the Kidney: Insights from Bench and Bedside.International journal of molecular sciences · 2021Review
- Trends of neglectedOne health (Amsterdam, Netherlands) · 2021Article
- Immunopathology of Acute Kidney Injury in Severe Malaria.Frontiers in immunology · 2021Review
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
objectiveAcute kidney injury (AKI) is a frequent presentation in malaria infections. Several cases of AKI that are accompanied by clinical symptoms of malaria infection, such as fever, nausea, respiratory distress, and anemia remain undiagnosed due to challenges in accurate diagnosis using peripheral blood microscopy and rapid diagnostic tests that are currently used in clinical settings. This is particularly true for P. vivax and P. knowlesi infections. As a result, these patients are not able to receive anti-malarial therapy in a timely manner. The objective of the present study was to investigate if patients presenting with AKI harbored any of the five human Plasmodium species (P. falciparum, P. vivax, P. knowlesi, P. malariae, and P. ovale) within their renal tissues.
resultsWe found that renal biopsies from malaria associated AKI patients harbor the human malaria parasites P. falciparum, P. vivax and P. knowlesi as mono- and mixed species infections. Presence of microvascular injury in a majority of the malaria associated AKI cases suggested vascular involvement of P. vivax and P. knowlesi. This research note also highlights P. knowlesi as an emerging pathogen in the Indian subcontinent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.