Evidence map›Paper›PMID 31959219›Full record

ArticleMolecular brain2020

Pcdhβ deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination.

Hirotaka Asai, Noriaki Ohkawa, Yoshito Saitoh, Khaled Ghandour, Emi Murayama, Hirofumi Nishizono, Mina Matsuo, Teruyoshi Hirayama, Ryosuke Kaneko, Shin-Ichi Muramatsu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecular brain, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Sleep and quiet wakefulness signify an idling brain hub for creative insights.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Selective engram coreactivation in idling brain inspires implicit learning.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Review
  15. Article
  16. The γ-Protocadherins Regulate the Survival of GABAergic Interneurons during Developmental Cell Death.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Hirotaka AsaiDepartment of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, 930-0194, Japan.
Noriaki OhkawaDepartment of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, 930-0194, Japan.
Yoshito SaitohDepartment of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, 930-0194, Japan.
Khaled GhandourDepartment of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, 930-0194, Japan.
Emi MurayamaDepartment of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, 930-0194, Japan.
Hirofumi NishizonoDivision of Animal Experimental Laboratory, Life Science Research Center, University of Toyama, Toyama, 930-0194, Japan.
Mina MatsuoDivision of Animal Experimental Laboratory, Life Science Research Center, University of Toyama, Toyama, 930-0194, Japan.
Teruyoshi HirayamaDepartment of Anatomy and Developmental Neurobiology, Tokushima University, Tokushima, 770-8501, Japan.
Ryosuke KanekoBioresource Center, Gunma University Graduate School of Medicine, Gunma, 371-8511, Japan.
Shin-Ichi MuramatsuDivision of Neurology, Department of Medicine, Jichi Medical University, Tochigi, 329-0498, Japan.
Takeshi YagiKOKORO-Biology Group, Laboratories for Integrated Biology, Graduate School of Frontier Biosciences, Osaka University, Osaka, 565-0871, Japan.
Kaoru InokuchiDepartment of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, 930-0194, Japan. inokuchi@med.u-toyama.ac.jp.ORCID 0000-0002-5393-3133
Japan Science and Technology Agency · JPUniversity of Toyama · JPGunma University · JPJichi Medical University · JPThe University of Osaka · JPTokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered protocadherins (Pcdhs), a large group of adhesion molecules, are important for axonal projections and dendritic spread, but little is known about how they influence neuronal activity. The Pcdhβ cluster is strongly expressed in the hippocampus, and in vivo Ca

Indexed as

AnimalsCA1 Region, HippocampalCadherinsCalciumConditioning, ClassicalDiscrimination LearningElectroshockExploratory BehaviorFearGenes, ReporterGenetic VectorsMaleMiceMice, KnockoutMicroscopy, FluorescenceNeuronsCadherinsCalciumProtein IsoformsCA1Ca2+ imagingClustered protocadherinContextual fear memoryDiscriminationEnsembleHippocampusPcdhβ

Identifiers

PMID31959219
PMCPMC6971911
OpenAlexW3001033241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.