Evidence map›Paper›PMID 31959214›Full record

ArticleRadiation oncology (London, England)2020

Squamous cell carcinoma (SCC) of the Pyriform sinus with multiple metachronous brain metastases, a case report.

Agostino Cristaudo, Antonio Stefanelli, Stefano Ursino, Durim Delishaj, Davide Baldaccini, Alessandra Gonnelli, Fabiola Paiar

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Agostino CristaudoDepartment of Radiotherapy, Azienda Ospedaliero-Universitaria di Ferrara, Via Aldo Moro, 44124, Ferrara, Cona, Italy. Agostino.cristaudo@gmail.com.ORCID http://orcid.org/0000-0002-9387-1109
Antonio StefanelliDepartment of Radiotherapy, Azienda Ospedaliero-Universitaria di Ferrara, Via Aldo Moro, 44124, Ferrara, Cona, Italy.
Stefano UrsinoDepartment of Radiotherapy, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Durim DelishajDepartment of Radiation Oncology, "A. Manzoni" Hospital, Lecco, Italy.
Davide BaldacciniDepartment of Radiotherapy, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Alessandra GonnelliDepartment of Radiotherapy, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Fabiola PaiarDepartment of Radiotherapy, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Azienda Ospedaliera Universitaria Pisana · ITAlessandro Manzoni Hospital · ITArcispedale Sant'Anna · ITAzienda Unità Sanitaria Locale di Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDistant Metastases from Head and Neck Squamous cell carcinomas are uncommon (9-11%) and they are usually found in the lung and less frequently in the liver, kidney and adrenals. Central nervous system (CNS) metastases are extremely rare (2-8%), and they are described mainly in patients who already have extracranial metastases. So there's scarcity of data about their optimal management . METHODS AND

resultsA patient presented CNS metastases after having been successfully treated with induction chemotherapy and definitive radiotherapy for a pyriform sinus carcinoma. The patient's work up, treatment and outcome are described.

conclusionsCNS metastases from Head and Neck carcinomas are exceptionally rare. Nevertheless, clinicians should be alert of neurological symptoms in these patients, in order to set up a timely assessment and treatment. Secondarily, given the rarity of this condition, additional research on this topic is warranted in order to improve therapeutic strategies and outcomes of such patients.

Indexed as

BrainBrain NeoplasmsCarcinoma, Squamous CellFatal OutcomeFemaleHumansHypopharyngeal NeoplasmsMiddle AgedPalliative CarePyriform SinusBrainHead and neck carcinomaMetastasesRadiotherapy

Identifiers

PMID31959214
PMCPMC6971903
OpenAlexW3013311692

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.