Evidence map›Paper›PMID 31959151›Full record

ArticleBMC public health2020

Healthy Options: study protocol and baseline characteristics for a cluster randomized controlled trial of group psychotherapy for perinatal women living with HIV and depression in Tanzania.

Mary C Smith Fawzi, Hellen Siril, Elysia Larson, Zenaice Aloyce, Ricardo Araya, Anna Kaale, Janeth Kamala, Muhummed Nadeem Kasmani, Amina Komba, Anna Minja and 5 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02039973 (Healthy Options), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02039973 nacompletednot on this map

Healthy Options: Group Psychotherapy for HIV-positive Depressed Perinatal Women.

TypeinterventionalSponsorHarvard Medical School (HMS and HSDM)Ran2013 to 2017Enrolled742ConditionsDepressionArmsTask-sharing approach to group therapy, Enhanced standard of care
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Mary C Smith FawziDepartment of Global Health and Social Medicine, Harvard Medical School, 641 Huntington Ave., Boston, MA, 02115, USA. mksfawzi@msn.com.
Hellen SirilManagement and Development for Health, Plot #802 Mwai Kibaki Road, Mikocheni, Dar es Salaam, Tanzania.
Elysia LarsonDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Boston, MA, 02115, USA.
Zenaice AloyceAfrica Academy for Public Health, Plot #802 Mwai Kibaki Road, Mikocheni, Dar es Salaam, Tanzania.
Ricardo ArayaKings College London, De Crespigny Park, London, SE5 8AF, UK.
Anna KaaleAfrica Academy for Public Health, Plot #802 Mwai Kibaki Road, Mikocheni, Dar es Salaam, Tanzania.
Janeth KamalaAfrica Academy for Public Health, Plot #802 Mwai Kibaki Road, Mikocheni, Dar es Salaam, Tanzania.
Muhummed Nadeem KasmaniDepartment of Global Health and Social Medicine, Harvard Medical School, 641 Huntington Ave., Boston, MA, 02115, USA.
Amina KombaAfrica Academy for Public Health, Plot #802 Mwai Kibaki Road, Mikocheni, Dar es Salaam, Tanzania.
Anna MinjaAfrica Academy for Public Health, Plot #802 Mwai Kibaki Road, Mikocheni, Dar es Salaam, Tanzania.
Angelina MwimbaAfrica Academy for Public Health, Plot #802 Mwai Kibaki Road, Mikocheni, Dar es Salaam, Tanzania.
Fileuka NgakongwaDepartment of Psychiatry and Mental Health, Muhimbili University of Health and Allied Sciences, United Nations Road, Dar es Salaam, Tanzania.
Magreat SombaAfrica Academy for Public Health, Plot #802 Mwai Kibaki Road, Mikocheni, Dar es Salaam, Tanzania.
Christopher R SudfeldDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Boston, MA, 02115, USA.
Sylvia F KaayaDepartment of Psychiatry and Mental Health, Muhimbili University of Health and Allied Sciences, United Nations Road, Dar es Salaam, Tanzania.
Africa Academy for Public Health · TZHarvard Global Health Institute · USMuhimbili University of Health and Allied Sciences · TZHarvard University · USKing's College London · GBManagement and Development for Health · TZ

Funding

BIOSTATISTICS/EPIDEMIOLOGY TRAINING GRANTS IN AIDST32AI007358 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Michael David Hughes · 1989 to 2026
$12.4M
Healthy Options: Group psychotherapy for HIV-positive depressed perinatal womenR01MH100338 · NIMH · HARVARD MEDICAL SCHOOL · PI KAAYA, SYLVIA, SMITH FAWZI, MARY CATHERINE · 2013 to 2017
$2.0M
NIAID NIH HHS T32 AI007358NIMH NIH HHS R01 MH100338NIMH NIH HHS R01-MH100338
6 · The paper itself

Abstract

backgroundPerinatal women accessing prevention of mother-to-child transmission of HIV (PMTCT) services are at an increased risk of depression; however, in Tanzania there is limited access to services provided by mental health professionals. This paper presents a protocol and baseline characteristics for a study evaluating a psychosocial support group intervention facilitated by lay community-based health workers (CBHWs) for perinatal women living with HIV and depression in Dar es Salaam.

methodsA cluster randomized controlled trial (RCT) is conducted comparing: 1) a psychosocial support group intervention; and 2) improved standard of mental health care. The study is implemented in reproductive and child health (RCH) centers providing PMTCT services. Baseline characteristics are presented by comparing sociodemographic characteristics and primary as well as secondary outcomes for the trial for intervention and control groups. The trial is registered under clinicaltrials.gov (NCT02039973).

resultsAmong 742 women enrolled, baseline characteristics were comparable for intervention and control groups, although more women in the control group had completed secondary school (25.2% versus 18.2%). Overall, findings suggest that the population is highly vulnerable with over 45% demonstrating food insecurity and 17% reporting intimate partner violence in the past 6 months.

conclusionsBaseline characteristics for the cluster RCT were comparable for intervention and control groups. The trial will examine the effectiveness of a psychosocial support group intervention for the treatment of depression among women living with HIV accessing PMTCT services. A reduction in the burden of depression in this vulnerable population has implications in the short-term for improved HIV-related outcomes and for potential long-term effects on child growth and development.

trial registrationThe trial is registered under clinicaltrials.gov (NCT02039973). Retrospectively registered on January 20, 2014.

Indexed as

Perinatal CarePsychotherapy, GroupAdolescentAdultDepressionFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalMiddle AgedPregnancyRandomized Controlled Trials as TopicSocioeconomic FactorsTanzaniaYoung AdultDepressionHIVInterventionPMTCTTreatmentWomen

Identifiers

PMID31959151
PMCPMC6971937
OpenAlexW3007233591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.