ArticleBMC psychiatry2020
The role of perceived stress and cognitive function on the relationship between neuroticism and depression among the elderly: a structural equation model approach.
Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02131181 (Incidence, Long- Term Outcome and Factor Related to Non- Cardiac Postoperative Delirium in Elderly Patients), which is not on this map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Incidence, Long- Term Outcome and Factor Related to Non- Cardiac Postoperative Delirium in Elderly Patients (POD-I)
Who cites it
28 citing papers in PubMed, 68 citations in OpenAlex.
- Trial
- Effects of Sodium Benzoate, a D-Amino Acid Oxidase Inhibitor, on Perceived Stress and Cognitive Function Among Patients With Late-Life Depression: A Randomized, Double-Blind, Sertraline- and Placebo-Controlled Trial.The international journal of neuropsychopharmacology · 2022Trial
- Article
- Loving-kindness moderates the association between neuroticism and anxiety symptoms among Thai older adults.Narra J · 2026Article
- Network analysis on depressive symptoms and big five personality traits of community elderly over 60 years old: a cross-sectional study.Frontiers in psychiatry · 2025Article
- The Effect of Psychological Resilience on Cognitive Decline in Community-Dwelling Older Adults: The Korean Frailty and Aging Cohort Study.Korean journal of family medicine · 2024Article
- The Relationship between Big Five Personality Traits and Depression in the German-Speaking D-A-CH Region Including an Investigation of Potential Moderators and Mediators.European journal of investigation in health, psychology and education · 2024Article
- The Association Between Multidimensional Influencing Factors and Depressive Symptoms in Chinese Adolescents - Beijing Municipality, China, July 2022-April 2023.China CDC weekly · 2024Article
- Article
- Relationship between perceived social support and disability with the mediating role of perceived stress among older adults.BMC geriatrics · 2024Article
- Effects of the mindfulness program for male substance abusers in Thailand on stress, deliberate self-harm, and drug abstinence intention: A repeated-measure design.Belitung nursing journal · 2024Article
- The chain mediating effects of resilience and perceived social support in the relationship between perceived stress and depression in patients with COVID-19.Frontiers in psychology · 2024Article
- Depression and Its Associated Factors among Undergraduate Engineering Students: A Cross-Sectional Survey in Thailand.Healthcare (Basel, Switzerland) · 2023Article
- Effects of Neuroticism on Differences in Symptom Structure of Life Satisfaction and Depression-Anxiety among College Students: A Network Analysis.Behavioral sciences (Basel, Switzerland) · 2023Article
- Mediating role of coping styles on the relationship between personality types and mental disorders in cardiovascular patients: a cross-sectional study in Iran.BMC psychiatry · 2023Article
- Association of Stress With Cognitive Function Among Older Black and White US Adults.JAMA network open · 2023Article
- Different Effects of Perceived Social Support on the Relationship between Perceived Stress and Depression among University Students with Borderline Personality Disorder Symptoms: A Multigroup Mediation Analysis.Healthcare (Basel, Switzerland) · 2022Article
- Role of Traumatic Events and Motivational Structure in Ambiguity Tolerance of Irritable Bowel Syndrome.Middle East journal of digestive diseases · 2022Article
- Role of neuroticism and perceived stress on quality of life among patients with dry eye disease.Scientific reports · 2022Observational
- Fear of COVID-19 and Perceived Stress: The Mediating Roles of Neuroticism and Perceived Social Support.Healthcare (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression comprises common psychological problems, and has been strongly related to neuroticism and perceived stress. While neuroticism has been shown to have a direct effect on depression, it also has an indirect effect via perceived stress. Among the elderly, cognitive function produces influences that should not be overlooked when investigating depression. This study aimed to determine the role of mediating effects of perceived stress as well as cognitive function on neuroticism and depression among elderly patients.
methodsThis research constituted a secondary analysis, with data collected during the pre-operative period of 429 elderly individuals undergoing elective, noncardiac surgery. The evaluation included the Perceived Stress Scale, the Neuroticism Inventory, the Montreal Cognitive Assessment, and the Geriatric Depression Scale. Structural equation modeling was used to investigate the hypothesized model.
resultsNeuroticism exhibited a significant indirect effect on perceived stress via depression and cognition (β = 0.162, 95% CI 0.026, 0.322, p = .002). Neuroticism initially had a direct effect on depression (β = 0.766, 95% CI 0.675, 0.843 p = 0.003); thereafter, it was reduced after covariates were added (β = 0.557, 95% CI 0.432, 0.668 p = 0.002). Based on this model, the total variance explained by this model was 67%, and the model showed an acceptable fit with the data.
conclusionsBoth perceived stress and cognitive function partially mediated the effect of neuroticism on depression, with perceived stress exhibiting a greater effect.
trial registrationThe study protocol has been registered at Clinicaltrials.gov under registered number: NCT02131181.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.